GENERAL ANESTHESIA

This study looked at whether dobutamine, a drug that helps the heart pump stronger, improves outcomes for septic shock patients undergoing surgery. Septic shock is a life-threatening condition where blood pressure drops dangerously low. The study included 584 adults having surger…

This study tested two ways of using a breathing machine during emergency abdominal surgery. One method used higher pressure to open the lungs, while the other used lower pressure to avoid overstretching. The goal was to see which approach reduced breathing failure and death after…

This study tested an opioid-free anesthesia method using esketamine for people having lung nodule surgery. 84 adults were randomly assigned to receive either esketamine or standard opioid anesthesia. The main goal was to see if esketamine improved lung function during surgery. Th…

This study tested a new drug called HSK3486 to see if it works as well as the standard drug propofol for putting adults to sleep before planned surgery. 465 adults having non-emergency surgery took part. The goal was to see if HSK3486 can safely induce anesthesia with fewer side …

This study tested a new medicine called HSK3486 to see if it works as well as a standard drug (propofol) for putting adults to sleep before planned surgery. About 400 people took part. The goal was to safely and effectively start anesthesia without needing extra rescue drugs.

This study tested whether avoiding opioids during gallbladder surgery could improve recovery. 101 adults were randomly assigned to receive either opioid-free anesthesia (using lidocaine and dexmedetomidine) or standard opioid-based anesthesia. The opioid-free group reported less …

This study tested a special monitor that tracks the body's pain balance during general anesthesia for laparoscopic surgery. The goal was to see if using this monitor to adjust pain medicine could reduce side effects like low blood pressure or slow heart rate. 37 adults having gal…

This study tested a newer sedative called ciprofol against the standard drug propofol for patients undergoing a minimally invasive heart valve replacement (TAVR). The goal was to see if ciprofol causes fewer drops in blood pressure and less injection pain. 124 older adults (ages …

This study tested whether giving magnesium sulfate during laparoscopic hysterectomy (a type of keyhole surgery to remove the uterus) can lower the amount of strong painkillers (opioids) needed during and after the operation. Sixty women aged 20-70 participated. The goal was to se…

This study looked at 60 children aged 3-8 who needed a procedure to close a hole in their heart. Researchers compared full general anesthesia to a lighter sedation with two medicines (dexmedetomidine and ketamine) plus numbing at the catheter site. They measured heart rate and bl…

This study looked at 60 adults having leg surgery with a tourniquet to see if spinal anesthesia or general anesthesia keeps more blood flowing to the leg. Researchers used a special light sensor to measure oxygen levels in the tissue. The goal was to find out which method might r…

This study looked at 100 pregnant women having planned C-sections to see if the time from incision to delivery affects the baby's umbilical cord blood gas levels (pH and base excess), which are markers of newborn well-being. Researchers compared women who had general anesthesia v…

This study looked at whether a simple scoring system (PRST) can accurately measure how deep a patient's anesthesia is during surgery. Researchers compared it to a standard brain-wave monitor (BIS) in 183 adults having elective surgery. The goal was to see if the PRST score alone …

This study followed 204 adults who had a kidney removed to find out why some develop chronic pain lasting months or years. Researchers measured pain levels right after surgery, at 3 months, and at 1 year. They also looked at factors like age, weight, and smoking to see which ones…

This study looked at how spinal and general anesthesia affect penile length in 200 adult men undergoing urological surgery. Researchers measured penile length and asked surgeons how satisfied they were with the surgical conditions. The goal was to see if the type of anesthesia ma…

This study looked at 78 older adults (65+) having gallbladder surgery to see if different levels of pressure from the breathing machine (called PEEP) affect blood flow and brain function. Researchers measured blood flow in the body and brain, and tested memory and thinking before…

This study looked at whether ultrasound can help doctors see what's in a child's stomach before emergency surgery. Knowing this helps them choose the safest way to give anesthesia and reduce the risk of stomach contents entering the lungs. The study included 146 children and aime…

This study looked at whether a new sedative drug called HSK3486 has abuse potential, meaning if people might misuse it. It involved 43 healthy adults who occasionally use central nervous system depressants. The goal was to compare HSK3486's effects to another sedative, propofol, …

This study looked at two different brands of stainless steel crowns used to fix cavities in children aged 2 to 8 years old. All children had their dental work done under general anesthesia. Researchers checked how well the crowns stayed in place and kept the gums healthy, and als…

This study tested a new way of removing a breathing tube after digestive surgery to see if it prevents low oxygen levels. About 208 adults having surgery lasting over an hour were randomly assigned to either the standard method or a method that keeps positive pressure on the lung…

This study looked at 110 children aged 2-10 having surgery under general anesthesia. It compared two common breathing machine modes (volume-controlled vs. pressure-controlled) to see which one causes less lung collapse (atelectasis). Doctors used lung ultrasound to check for coll…

This study looked at whether storing a breathing tube (laryngeal mask airway) at a cooler temperature (10-12°C) versus room temperature (22-25°C) affects sore throat after surgery. 172 adults having elective surgery under general anesthesia took part. Researchers checked for sore…

This study looked at a new measure called eMAC that combines the effects of different anesthesia drugs to gauge how deep a patient's anesthesia is during surgery. Researchers observed 60 adults having planned surgeries and recorded standard anesthesia readings without changing an…