FATIGUE

This study tests whether laser acupuncture (using low-level light instead of needles) can ease fatigue and improve quality of life in adults with end-stage kidney disease who are on dialysis. Fifty participants will receive either real laser acupuncture or a sham treatment during…

This study tests whether a relaxation method called autogenic training can help people on hemodialysis who suffer from restless leg syndrome, poor sleep, and fatigue. About 54 adults aged 45-55 will practice guided relaxation exercises for 8 weeks. Researchers will measure change…

This study tests whether walking with a robot dog can improve sleep, reduce tiredness, and boost quality of life in children aged 2-7 who are being treated for cancer. Forty kids will either walk with a robot dog or receive standard care. The goal is to see if this fun, safe acti…

This study looks at whether certain health and wellness products can help reduce fatigue in women going through menopause. About 550 women aged 35-60 who have at least two menopausal symptoms will take either the product or a placebo. The goal is to see if these products improve …

This study tests whether breathing in the scent of agarwood (a fragrant wood) while sleeping can help hospital staff feel less tired and sleep better. About 78 hospital workers will use either an agarwood sachet or a placebo (almond oil) sachet near their bed for 7 nights. The go…

This study looks at whether doing art activities (like painting or drawing) can help people with blood cancers feel less tired and anxious, and improve their quality of life. About 52 adults getting chemotherapy will take part, with half doing art therapy for two weeks and the ot…

This study tests whether personalized coaching on sleep, diet, and exercise can help emergency medicine residents stay alert and recover better during overnight shifts. Thirty residents will either receive one-on-one coaching or standard tips. Their sleep, reaction time, and well…

This study tests two simple, drug-free methods—reflexology (foot massage) and progressive muscle relaxation—to see which better reduces fatigue in people on dialysis. Sixty adults aged 50-70 with moderate to severe fatigue will be randomly assigned to one of the two treatments or…

This study tests if electroacupuncture (a type of acupuncture with mild electric pulses) can reduce a group of common symptoms—pain, tiredness, sleep trouble, anxiety, depression, and brain fog—in breast cancer survivors. About 228 women who have finished active cancer treatment …

This study tests whether a smartphone app that teaches self-guided acupressure can help reduce fatigue and itching, and improve sleep, in people receiving hemodialysis. About 70 adults on dialysis will be randomly assigned to use the app daily for 4 weeks or to receive usual care…

This early-stage study tests whether a non-invasive brain stimulation technique called rTMS is safe and can help ease depression and fatigue in adults with multiple sclerosis (MS). About 20 participants with MS and moderate-to-severe depression will receive daily rTMS sessions fo…

This study tests a web-based program designed to help people with advanced cancer manage symptoms like depression, pain, fatigue, and sleep problems, while also supporting their caregivers. About 40 patients and their partners will use the program to track symptoms and get person…

This study tests whether modafinil, a drug that promotes wakefulness, can reduce severe fatigue in people with Crohn's disease or ulcerative colitis. About 70 adults with long-term fatigue will receive either modafinil or a placebo for 12 weeks. The main goal is to see if a large…

This study looks at whether a supplement called Alpha Brain can improve thinking, alertness, and mood in healthy adults who haven't slept much. About 34 people will take the supplement or a placebo on different days and do tests. The goal is to see if it helps with focus and redu…

This study will test whether a 16-week Pilates program done at home via video calls can improve walking, balance, fatigue, and pain in people with multiple sclerosis (MS). About 50 adults with mild to moderate MS will be assigned to either the Pilates group or a waitlist. Researc…

This early-phase study tests whether bupropion, a drug used for smoking cessation and depression, can reduce severe fatigue in 16 adults with end-stage kidney disease on hemodialysis. Participants take the pill three times a week during dialysis for 8 weeks and report their fatig…

This study tests if shining a special light on muscles before using electrical stimulation can reduce tiredness, soreness, and muscle damage. Healthy adults aged 18-45 will receive either real or fake light treatment, then undergo a series of electrical muscle contractions. Resea…

This study looks at how muscle loss (sarcopenia) is related to tiredness and dizziness when standing up in people aged 65 and older. Researchers will compare two groups: those with sarcopenia and those without. The goal is to better understand these connections to improve care fo…

This study tests whether a structured educational program called 'Stay Awake, Stay Alive' can reduce drowsy driving among college students in Nevada. About 72 students will be randomly assigned to either this new program or a standard AAA education program. They will attend four …

This pilot study tests whether a mild electrical stimulation called TENS can change brain activity in people with Multiple Sclerosis (MS) who have fatigue and walking problems. Researchers will use brain scans (fMRI) to see how the brain responds during stimulation. The goal is t…