ENDOMETRIAL CARCINOMA

This early-phase trial tests a personalized vaccine made using quantum computing for 40 people with high-risk or returning endometrial cancer. The vaccine is designed to train the immune system to attack each person's unique tumor. The main goals are to check safety and see if th…

This early-phase study tests the safety and best dose of the drug veliparib when given with standard chemotherapy (carboplatin and paclitaxel) in people with advanced solid tumors that also have liver or kidney problems. The goal is to find a safe dose and understand how the body…

This study tests a drug called pembrolizumab in about 1,600 people with advanced solid tumors (like anal, bile duct, or endometrial cancer) that have stopped responding to standard treatments. The goal is to see if the drug can shrink or control the tumors. Participants receive p…

This study tests whether adding pterostilbene (an antioxidant from blueberries) to the hormone drug megestrol acetate works better than megestrol alone in treating endometrial cancer or precancerous changes. About 44 women scheduled for hysterectomy will receive the treatment bef…

This study planned to test two drugs, bemarituzumab and bevacizumab, together in people with advanced endometrial, ovarian, or cervical cancers that have a specific protein (FGFR2b). The goal was to find the safest dose and see if the combination could shrink tumors or slow their…

This study follows women with gynecologic cancers who have had a pelvic exenteration—a surgery removing the lower colon, rectum, and bladder. Researchers track complications, quality of life, and survival to learn which surgical methods work best. The goal is to improve recovery …