ENDOMETRIAL CARCINOMA

This study tests a drug called enfortumab vedotin in up to 12 women with advanced endometrial cancer that has worsened after prior treatments, including immunotherapy. The drug targets a protein on cancer cells to deliver a toxin that kills them. Researchers will measure how many…

This phase 3 trial will test a new drug called mocertatug rezetecan against standard chemotherapy in 600 people with endometrial cancer that has progressed after platinum-based chemo and immunotherapy. The goal is to see if the new drug shrinks tumors or delays cancer growth bett…

This study tests whether taking low-dose aspirin can lower inflammation in the womb lining and help prevent endometrial cancer. It involves 25 postmenopausal women who have non-atrophic endometrial changes and pain. Participants will be randomly assigned to take aspirin or not, a…

This study tests a new way to deliver radiation therapy for endometrial cancer using daily MRI scans to guide the beam. The goal is to give a higher dose of radiation to the tumor while sparing nearby organs like the bowel and bladder. Thirty participants will receive 15 sessions…

This study asks Black women aged 45 and older how they feel about using a vaginal fluid sample to test for DNA markers of endometrial cancer. The goal is to understand if women would accept this as a screening method. No treatment is given—just a 30-minute virtual interview to ga…

This study looks at how well patients do after surgery that removes both advanced gynecologic cancers and the major blood vessels they have grown into. Researchers will track 130 participants for up to 5 years to see survival rates and how long it takes for the cancer to return. …