Aspirin may fight Cancer-Causing inflammation in the womb

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * PRE-REGISTRATION: Postmenopausal women * PRE-REGISTRATION: Transvaginal ultrasound * PRE-REGISTRATION: Scheduled endometrial biopsy * PRE-REGISTRATION: Provide risk factor survey * REGISTRATION: Postmenopausal (defined clinically by no period for over 1 year or postmenopausal follicle-stimulating hormone \[FSH\], estradiol, or anti-Mullerian hormone \[AMH\] levels due to natural, medical, or surgical causes) * REGISTRATION: Have pain (an indicator of inflammation) and other findings warranting endometrial sampling (postmenopausal bleeding \[PMB\], incidentally noted thickened endometrium \> 4mm on ultrasound, obesity, fibroids) * REGISTRATION: Capable of providing informed consent * REGISTRATION: Understands English or Spanish language for consent and questionnaires * REGISTRATION: Ability to complete questionnaire(s) by themselves or with assistance * REGISTRATION: Willingness to provide mandatory blood specimens for correlative research * REGISTRATION: Willingness to provide mandatory tissue specimens for correlative research * REGISTRATION: Willingness to provide mandatory urine sample for correlative research Exclusion Criteria: * PRE-REGISTRATION: Not postmenopausal person born with uterus * PRE-REGISTRATION: Atrophic endometrium * PRE-REGISTRATION: No uterus * PRE-REGISTRATION: Malignancy found * REGISTRATION: Patients with previous hysterectomy (removal of the uterus) * REGISTRATION: Atrophic endometrium on endometrial sampling performed clinically * REGISTRATION: Patients from outside the Mayo Clinic Comprehensive Cancer Center (MCCCC) area * REGISTRATION: Clinically contraindicated to discontinue use of anticoagulation other than aspirin * REGISTRATION: Contraindication to use of nonsteroidal anti-inflammatory drugs (NSAIDs) or previous adverse reaction or intolerance to NSAIDs * REGISTRATION: History of uterine, cervical, or ovarian cancers or precancers (endometrial hyperplasia, cervical dysplasia, fallopian tube intraepithelial carcinoma)