Uterine cancer survivors: how does treatment affect daily life?
NCT ID NCT04634617
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at pelvic floor problems and quality of life in people who survived uterine cancer. Researchers will use questionnaires to gather information from about 310 survivors treated with surgery at MD Anderson between 2006 and 2017. The goal is to better understand how common these issues are and how they affect survivors' lives.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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310 people
The number who actually took part.
- Started
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Jan 2020
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with uterine cancer treated with surgery +/- radiation at MD Anderson between 2006 and 2017 and patients who have never been diagnosed with any cancer other than non-melanomatous skin cancers and have undergone hysterectomy/bilateral-salpingo-oophorectomy (BSO) for benign reasons between 2006 and 2017
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with uterine cancer (including endometrial and uterine carcinoma or sarcoma) treated with surgery +/- radiation at MD Anderson between 2006 and 2017 * Eligible surgeries include laparoscopic or robotic assisted abdominal total hysterectomy, total abdominal hysterectomy, and vaginal hysterectomy with or without pelvic node dissection, with or without omentectomy or omental biopsies * In addition, patients must have had all WITH bilateral-salpingo-oophorectomy (BSO), either during their surgery or in a previous or subsequent (within 3 months of endometrial cancer diagnosis) surgery * Patients have had at least one year of follow-up * Patients have not had any recurrence of disease * Patients must be able to complete the survey of their own volition * Patients must be able to read and speak English fluently * CONTROL GROUP: Patients have never been diagnosed with any cancer other than non-melanomatous skin cancers * CONTROL GROUP: Patient has undergone hysterectomy/BSO for benign reasons between 2006 and 2017 * CONTROL GROUP: Patients must be able to complete the survey of their own volition * CONTROL GROUP: Patients must be able to speak and read English fluently Exclusion Criteria: * Patients with cancer recurrence, as this will affect their current quality of life * Patients with additional pelvic surgery at the time of their hysterectomy (for example pelvic exenteration, urostomy placement, etc.) * Patients with a secondary primary cancer (including cervical cancer), as this will affect their current quality of life. Patients may have either squamous cell or basal cell carcinoma of the skin * Neurocognitive deficits that render patients unable to complete the survey on their own * Patients who have not yet had removal of their bilateral ovaries * Preoperative radiotherapy prior to hysterectomy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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