DIFFERENTIATED THYROID CANCER
Clinical trials for DIFFERENTIATED THYROID CANCER explained in plain language.
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New combo therapy aims to boost radioactive iodine's power against stubborn thyroid cancer
Disease control Recruiting nowThis study tests whether the drug larotrectinib can make thyroid cancer cells more sensitive to radioactive iodine therapy. It includes children and adults with a specific genetic change (NTRK fusion) whose cancer has spread to the lungs. The goal is to see if this combination ca…
Matched conditions: DIFFERENTIATED THYROID CANCER
Phase: PHASE2 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated May 26, 2026 03:45 UTC
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Less surgery may be just as good for Low-Risk thyroid cancer
Disease control Recruiting nowThis study looks at whether removing only half of the thyroid gland (hemithyroidectomy) works as well as removing the whole gland (total thyroidectomy) for people with low-risk thyroid cancer. About 456 adults with early-stage thyroid cancer will be randomly assigned to one of th…
Matched conditions: DIFFERENTIATED THYROID CANCER
Phase: NA • Sponsor: University College, London • Aim: Disease control
Last updated May 26, 2026 02:48 UTC
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New combo therapy may boost radioactive iodine's power against childhood thyroid cancer
Disease control Recruiting nowThis study tests whether giving targeted drugs before radioactive iodine (RAI) can make thyroid cancer tumors absorb more RAI, potentially improving treatment. About 32 children and teens with metastatic differentiated thyroid cancer and specific genetic mutations will receive ta…
Matched conditions: DIFFERENTIATED THYROID CANCER
Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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New pill combo targets Hard-to-Treat cancers in early trial
Disease control Recruiting nowThis study tests a new experimental drug (PF-07799544) combined with another drug (PF-07799933) in adults with advanced solid tumors that have a specific gene change called BRAF V600. The goal is to see if the combination is safe and can shrink or control the cancer. Participants…
Matched conditions: DIFFERENTIATED THYROID CANCER
Phase: PHASE1 • Sponsor: Pfizer • Aim: Disease control
Last updated May 06, 2026 16:13 UTC
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New combo therapy aims to boost radioactive iodine success in young thyroid cancer patients
Disease control Recruiting nowThis study tests whether giving a drug called selpercatinib for 6 months before radioactive iodine therapy can improve treatment outcomes in children, teens, and young adults (ages 2-25) with a specific genetic form of thyroid cancer (RET fusion). The goal is to make the cancer a…
Matched conditions: DIFFERENTIATED THYROID CANCER
Phase: PHASE2 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated May 05, 2026 11:55 UTC
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New PET tracer could spot hidden thyroid cancer better than current scans
Diagnosis Recruiting nowThis study compares a new imaging agent, F-18 TFB, to the standard FDG PET/CT scan for finding thyroid cancer in 50 people who have had surgery and radioactive iodine therapy but still have high thyroglobulin levels. F-18 TFB targets thyroid cells specifically, potentially offeri…
Matched conditions: DIFFERENTIATED THYROID CANCER
Phase: NA • Sponsor: Ankara University • Aim: Diagnosis
Last updated May 26, 2026 03:36 UTC
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Thyroid cancer study: does a low iodine diet boost radioactive iodine absorption?
Knowledge-focused Recruiting nowThis study looks at how a 7-day low iodine diet changes the amount of radioactive iodine absorbed by the body in people who have had their thyroid removed due to thyroid cancer. About 25 adults will take a small dose of radioactive iodine before and after the diet to measure the …
Matched conditions: DIFFERENTIATED THYROID CANCER
Phase: NA • Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated May 26, 2026 03:51 UTC
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Immune drug studied in thyroid cancer before surgery
Knowledge-focused Recruiting nowThis study tests whether giving the immune-boosting drug pembrolizumab before surgery can help understand how the immune system fights thyroid cancer. About 25 adults with high-risk differentiated thyroid cancer will receive the drug and then have surgery. The main goal is to lea…
Matched conditions: DIFFERENTIATED THYROID CANCER
Phase: PHASE2 • Sponsor: Istituti Clinici Scientifici Maugeri SpA • Aim: Knowledge-focused
Last updated May 26, 2026 03:37 UTC
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New model aims to predict thyroid surgery challenges before the first cut
Knowledge-focused Recruiting nowThis study aims to create a simple tool (called a nomogram) that helps doctors predict how difficult a specific type of thyroid cancer surgery will be before they start. The surgery, called transoral and submental thyroidectomy, is done through the mouth and under the chin to avo…
Matched conditions: DIFFERENTIATED THYROID CANCER
Sponsor: Shanghai 6th People's Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 03:37 UTC