New PET scan could improve detection of metastatic thyroid cancer
NCT ID NCT06961084
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares a newer type of scan (I-124 PET/CT) to the standard scan (I-123 whole body imaging) for finding thyroid cancer that has spread. About 62 people with thyroid cancer will get both scans, and researchers will see if the new scan is more accurate. The goal is to improve how doctors detect and manage thyroid cancer.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 62 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Apr 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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13 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age \>= 13 years. 2. Histopathologically confirmed differentiated or poorly differentiated thyroid cancer. 3. Meeting criteria for one of the following two populations: 1. American Thyroid Association (ATA) intermediate or high-risk thyroid cancer and planning on treatment using I-131. 2. Metastatic disease on imaging (CT, MRI, ultrasound or FDG PET), and considering localized therapy such as surgery and radiation therapy. 4. Undergone total thyroidectomy. 5. Planned I-123 imaging within 45 days after enrollment. 6. Ability to understand a written informed consent document, and the willingness to sign it. Exclusion Criteria: 1. Unlikely to comply with study procedures, restrictions and requirements and judged by the Investigator to be unsuitable for participation. 2. Known pregnancy.
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
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Genom att skicka in godkänner du våra Användarvillkor
Locations
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94122, United States
Contact Email: •••••@•••••
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Other studies related to the condition(s) this trial covers.
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- Mapping how thyroid tumors spread and what surgery leaves behind
- Antibody-Drug conjugate targets TROP-2 in Hard-to-Treat thyroid cancers
- Can a video keep thyroid cancer patients on track after surgery?
- Can doctors safely watch small thyroid cancers instead of removing them?
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