New combo therapy may boost radioactive iodine's power against childhood thyroid cancer
NCT ID NCT05024929
First seen Nov 15, 2025 · Last updated May 21, 2026 · Updated 25 times
Summary
This study tests whether giving targeted drugs before radioactive iodine (RAI) can make thyroid cancer tumors absorb more RAI, potentially improving treatment. About 32 children and teens with metastatic differentiated thyroid cancer and specific genetic mutations will receive targeted therapy for 4-6 weeks, then RAI. The goal is to see if this approach increases RAI uptake in lung tumors.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Boston Children's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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Children's Hospital Westmead
RECRUITINGSydney, New South Wales, Australia
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Children's Hospital of Philadelphia
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Emory University School of Medicine
RECRUITINGAtlanta, Georgia, 30322, United States
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MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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Seattle Children's Hospital
RECRUITINGSeattle, Washington, 98105, United States
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St. Jude Children's Research Hospital
RECRUITINGMemphis, Tennessee, 38105, United States
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Texas Children's Hospital
RECRUITINGHouston, Texas, 77030, United States
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University of California San Francisco
RECRUITINGSan Francisco, California, 94143, United States
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