DEGENERATIVE DISC DISEASE

This study tests a device called PCSS used with neck fusion surgery for people with degenerative disc disease in the neck. About 236 adults aged 18-80 who need surgery on three neck levels are included. The goal is to see if the device helps bones fuse better and is safe compared…

This study tests a special bone graft called Virtuos in people having spinal fusion surgery for degenerative disc disease. The graft is made from donated human cells and is meant to help the bones in the spine fuse together better. Researchers will check if the fusion is successf…

This study tests whether a new bone graft material (P-15L) works as well as the standard bone graft for spinal fusion surgery in people with degenerative disc disease. About 290 adults aged 22-80 with back and leg pain will be enrolled. The goal is to see if the new graft helps b…

This study looks at three different types of implants used in spine fusion surgery for people with degenerative disc disease or spondylolisthesis. About 300 adults aged 18-80 will receive one of the implants during a procedure called XLIF. The goal is to see which implant leads t…

This study looks at how safe and effective special spinal implants are for people with degenerative disc disease or unstable neck bones. About 150 adults who need neck surgery will get these implants and be followed for 24 months. The goal is to see if the bones fuse correctly an…

This study tests a single injection of AGA111 given directly into the spine during lumbar fusion surgery for people with degenerative disc disease. The goal is to see if it improves bone healing and reduces pain and disability compared to a placebo. About 412 adults aged 18 to 80…

This study looks at how safe and effective NuVasive spine implants are for adults with degenerative back problems like disc disease, scoliosis, or spinal stenosis. About 1,050 participants will be followed for up to 24 months to check for complications, bone fusion, and pain reli…

This study looks at a new material called Natural Matrix Protein (NMP) fibers used during spine fusion surgery. The goal is to see if these fibers help bones fuse together safely and effectively in people with degenerative disc disease, spinal stenosis, or spondylolisthesis. Abou…

This study follows 158 people who already received a Simplify Disc implant in their neck to see how safe and effective it is over 10 years. Researchers will measure neck function, nerve health, and whether any further surgery or serious problems occur. The goal is to confirm the …

This study looks at how safe and effective a special metal implant system is for stabilizing the neck and upper back after surgery. About 150 adults who need this surgery for injuries, tumors, or spine problems will take part. Researchers will track complications, X-ray results, …

This study follows 131 people who already received the Simplify Disc implant for cervical disc disease. Researchers will check how well the disc works and if any problems arise over 10 years. The goal is to see if patients have less neck pain and avoid further surgery.

This study looks at how well a special implant (Tritanium® C cage) helps bones in the neck fuse together after surgery. About 50 adults with worn-out or herniated neck discs will get the implant and be followed for two years. The main goal is to see if the bones heal properly, an…

This study compares two types of implants used in spine surgery: a new titanium cage with a special rough surface and a standard plastic cage. About 100 adults with spine problems like narrowing of the spinal canal or worn-out discs will be randomly assigned to receive one of the…

This study aimed to compare two treatments for chronic low back pain caused by worn-out discs: injections of a person's own bone marrow stem cells versus standard steroid injections. It was designed for adults with long-term pain who had not improved with other treatments. Howeve…

This study reviews medical records from about 200 people who received a Prodisc C Vivo device at two levels in the neck to treat degenerative disc disease. The goal is to see how safe the device is and how well it works by tracking any additional surgeries needed and other health…

This study was designed to observe the safety and performance of the Arcadius XP L spinal implant in people with chronic low back pain from conditions like degenerative disc disease. It planned to follow 60 patients for at least one year after surgery, measuring pain and disabili…

This study follows 22 adults who have spine surgery (LLIF or ALIF) to see how long hip and leg weakness lasts. Researchers measure hip strength before surgery and again at 6 weeks, 12 weeks, and 6 months after. The goal is to learn the exact timing of when strength returns, which…

This study looks at three ways surgeons place screws in the spine: using a robot, using a navigation system, or doing it freehand. The goal is to see which method leads to fewer screws needing to be fixed or replaced within a year. About 932 adults with spine problems like disc d…