DEGENERATIVE DISC DISEASE
Clinical trials for DEGENERATIVE DISC DISEASE explained in plain language.
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Could a simple injection repair your Worn-Out spinal discs?
Disease control CompletedThis early-stage study tested whether injecting specially prepared disc cells directly into a damaged spinal disc could help people with chronic low back pain. It compared two different doses of the cell therapy against a placebo injection in 38 participants. The main goal was to…
Matched conditions: DEGENERATIVE DISC DISEASE
Phase: PHASE1 • Sponsor: DiscGenics, Inc. • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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New spinal implants tested for chronic back pain relief
Disease control CompletedThis study evaluated the safety and effectiveness of two expandable spinal implants (MLX and XLX ACR) for people with degenerative back conditions like disc disease and spondylolisthesis. Researchers followed 109 patients who had already received these implants during standard sp…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Stem cell bone graft tested to heal spinal fusions
Disease control CompletedThis study tested a special bone graft material containing stem cells, called Osteocel Plus, to see how well it helps spinal bones grow together after fusion surgery for severe back pain. Researchers followed 28 patients with degenerative disc disease for two years after surgery …
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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Stem cell graft aims to heal spinal fusions faster
Disease control CompletedThis study tested a special bone graft material containing stem cells, called Osteocel Plus, for use in spinal fusion surgery. The goal was to see if it helps the bones in the spine join together solidly after surgery for severe, long-term back pain. Researchers followed 19 patie…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Gel injection tested as potential fix for Worn-Out spinal discs
Disease control CompletedThis study tested a new gel implant system for people with long-term lower back pain caused by worn-out spinal discs. It involved 35 adults whose pain hadn't improved after at least six months of standard treatments like medication or physical therapy. The main goals were to see …
Matched conditions: DEGENERATIVE DISC DISEASE
Phase: NA • Sponsor: ReGelTec, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Can a new biologic gel help heal your spine after surgery?
Disease control CompletedThis study looked back at medical records and collected new data to see how well a biologic material called NMP™ worked when used during spine fusion surgery for lower back pain from worn-out discs. It involved 53 patients who had the surgery and checked a year later to see if th…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: Induce Biologics USA Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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New spinal implant tested to fuse painful backs
Disease control CompletedThis study tested a specific spinal implant device used in fusion surgery for people with painful, worn-out discs in their lower back. It followed 25 patients for two years after surgery to see how safe the device was and if it successfully helped the bones fuse together. The mai…
Matched conditions: DEGENERATIVE DISC DISEASE
Phase: NA • Sponsor: Invibio Ltd • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Stem cell bone graft aims to heal spinal fusions faster
Disease control CompletedThis study tested a special bone graft material containing stem cells, called Osteocel Plus, during a specific type of spinal fusion surgery (XLIF). The goal was to see if this material could help the spine bones fuse together solidly and potentially faster than other standard gr…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New spinal implant tested for safety and effectiveness
Disease control CompletedThis study tested the safety and performance of the Modulus ALIF system, a medical device used in spinal fusion surgery. Researchers followed 123 patients with degenerative disc disease, spondylolisthesis, or spinal stenosis who received the implant. They checked for complication…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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3D-Printed spine implant tested for back pain relief
Disease control CompletedThis study tested the safety and performance of a new 3D-printed titanium implant used during a specific type of spinal fusion surgery. It involved 36 adults with degenerative back conditions like disc disease or scoliosis. Researchers checked for complications, used CT scans to …
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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New spinal implant aims to ease chronic back pain
Symptom relief CompletedThis study tested a new spinal implant system designed to help people with degenerative back conditions like disc disease and scoliosis. It involved 75 adults who had spinal fusion surgery using the implant. Researchers followed patients for two years to see if the device was saf…
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Symptom relief
Last updated Apr 03, 2026 14:43 UTC
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New back surgery technique aims to ease pain with smaller incision
Symptom relief CompletedThis study tested a less invasive spinal fusion surgery for people with painful, worn-out discs in their lower back. The procedure uses a smaller incision than traditional surgery, aiming to reduce pain and disability after the operation. Researchers followed 77 patients for two …
Matched conditions: DEGENERATIVE DISC DISEASE
Sponsor: NuVasive • Aim: Symptom relief
Last updated Apr 02, 2026 14:57 UTC
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Back surgery pain study tests blocks vs. local numbing
Symptom relief CompletedThis study compared two methods for managing pain after spinal fusion surgery. It tested whether a specific nerve block given before surgery or a large dose of local numbing medicine given at the end worked better than standard care alone. Researchers measured patients' pain leve…
Matched conditions: DEGENERATIVE DISC DISEASE
Phase: PHASE2 • Sponsor: Rashmi Mueller • Aim: Symptom relief
Last updated Mar 02, 2026 15:24 UTC