COLORECTAL ADENOCARCINOMA
Clinical trials for COLORECTAL ADENOCARCINOMA explained in plain language.
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New hope for Tough-to-Treat colorectal cancer: drug combo under study
Disease control TerminatedThis study is for people with advanced colorectal cancer that has a specific genetic change called a KRAS mutation and has stopped responding to standard treatments. Researchers are testing the safety and effectiveness of combining two drugs, AVUTOMETINIB and cetuximab. The goal …
Matched conditions: COLORECTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: University of Chicago • Aim: Disease control
Last updated May 26, 2026 11:38 UTC
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Could vitamin D3 boost chemo for advanced colon cancer?
Disease control OngoingThis phase 3 trial tests whether adding high-dose vitamin D3 to standard chemotherapy and a targeted drug (bevacizumab) helps people with metastatic colorectal cancer live longer without their disease getting worse. The study includes 455 adults whose cancer has spread and who ha…
Matched conditions: COLORECTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 26, 2026 11:30 UTC
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New combo therapy aims to stall hard-to-treat colon cancer
Disease control OngoingThis study tests a two-drug combination (cabozantinib and nivolumab) in people with advanced colorectal cancer that is microsatellite stable (MSS) and has stopped responding to standard treatments. The goal is to see if the combination can control the cancer for at least 16 weeks…
Matched conditions: COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated May 26, 2026 11:28 UTC
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New drug cocktail shows promise for Tough-to-Treat colorectal cancer
Disease control OngoingThis study tests whether a combination of three drugs—temozolomide, cisplatin, and nivolumab—can shrink tumors in people with advanced colorectal cancer that has not responded to at least two prior treatments. The trial includes 18 adults whose cancer is mismatch repair-proficien…
Matched conditions: COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 26, 2026 11:27 UTC
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New combo therapy shows promise for hard-to-treat colorectal cancer
Disease control OngoingThis study tests whether adding an immunotherapy drug (nivolumab) to standard chemotherapy can help control or shrink metastatic colorectal cancer that has not responded to other treatments. About 80 adults with a specific type of colorectal cancer (pMMR/MSS) will receive this co…
Matched conditions: COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: University Hospital, Akershus • Aim: Disease control
Last updated May 26, 2026 11:25 UTC
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New combo therapy aims to control lung metastases in colorectal cancer patients
Disease control OngoingThis study looks at whether combining chemotherapy with surgery to remove lung tumors works better than either treatment alone for people with colorectal cancer that has spread to the lungs. About 40 adults with this condition will be grouped by risk level and receive different t…
Matched conditions: COLORECTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 11:24 UTC
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New cancer drug TST003 enters human trials for advanced tumors
Disease control OngoingThis study tests a new drug called TST003 in about 111 people with advanced solid tumors that have spread or cannot be removed by surgery. The main goals are to find a safe dose, check side effects, and see if the drug can shrink tumors. Participants receive the drug through a ve…
Matched conditions: COLORECTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Suzhou Transcenta Therapeutics Co., Ltd. • Aim: Disease control
Last updated May 26, 2026 11:09 UTC
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New hope for advanced colorectal cancer: does adding chemo to surgery improve survival?
Disease control OngoingThis study tests whether giving chemotherapy before and after surgery (plus heated chemotherapy during surgery) helps people with colorectal cancer that has spread to the abdomen lining live longer compared to surgery alone. About 358 adults with resectable cancer will be randoml…
Matched conditions: COLORECTAL ADENOCARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: Koen Rovers • Aim: Disease control
Last updated May 26, 2026 11:09 UTC