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Fewer cuts, same hope: new surgery for colon cancer tested

NCT ID NCT05953662

Disease control Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares a newer, less invasive surgery (reduced-port laparoscopy) to standard laparoscopic surgery for people with colon or upper rectal cancer. The goal is to see if the newer approach is as safe and effective, while possibly causing less pain and faster recovery. 500 adults aged 18-80 with non-metastatic colorectal cancer are taking part.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Reduced-port laparoscopic surgery
What this could lead to
If successful, this could offer a less invasive surgical option for colon and upper rectal cancer, potentially reducing pain, recovery time, and medical costs.
What could go wrong
This is a phase 2 study, so results are preliminary. The reduced-port technique is more difficult for surgeons and may not be safer or as effective as standard surgery. Long-term outcomes are not yet known.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 500 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2023

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18-80 years old; 2. Pathological diagnosis of colorectal adenocarcinoma (including high, medium and low-differentiated adenocarcinoma, excluded: mucinous adenocarcinoma, signet ring cell carcinoma); 3. Eastern Cooperative Oncology Group (ECOG) is 0-1 points; 4. Chest, whole abdomen, pelvic enhanced CT confirm colon or upper rectal cancer, without distant metastasis; 5. No other multiple primary tumors; 6. No organ dysfunction; 7. The patient and his/her family are able to understand the study protocol and are willing to participate in the study and sign informed consent. Exclusion Criteria: 1. Age \< 18, or \> 80 years old; 2. Combined with simultaneous or heterogeneous (within 5 years) malignant tumors; 3. Patients with intestinal obstruction, intestinal perforation, intestinal bleeding, etc. who require emergency surgery; 4. Joint organ resection is required; 5. ASA Class IV or V; 6. Suffering from a serious mental illness; 7. Patients with severe emphysema, interstitial pneumonia or ischemic heart disease, etc. who cannot tolerate surgery; 8. Continuous systemic steroid therapy within 1 months; 9. Patients or families are unable to understand the conditions and objectives of this study.

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Conditions

The condition(s) this trial relates to.

colorectal adenocarcinoma colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal neoplasm

Contacts and locations

Locations

  • The Sixth Affiliated Hospital, Sun Yatsen University

    Guangzhou, Guangdong, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.