Colonoscopy

This trial tests whether a low-volume lactulose drink can clean the bowel as well as the standard high-volume polyethylene glycol (PEG) solution before a colonoscopy. Adults aged 45 to 75 scheduled for routine outpatient colonoscopy are randomly assigned to take either lactulose …

Colonoscopy can be uncomfortable, especially for older adults. This trial compares two ways to expand the colon during the exam, warm water exchange versus standard gas insufflation, each tested with and without anesthesia. Researchers randomly assign 200 participants aged 55 and…

Doctors often judge colonoscopy quality by how many screening patients have adenomas found, but that measure leaves out people who get colonoscopies for surveillance or symptoms. This study at multiple hospitals in Taiwan compares the screening-only adenoma detection rate with a …

Researchers are testing two new bowel-cleansing solutions, GNS-212-E1 and GNS-212-E2, against a standard polyethylene glycol (PEG) solution. The trial enrolls about 318 adults scheduled for a colonoscopy. Participants take their assigned solution the evening before and the mornin…

This study tested whether an artificial intelligence system called CAD EYE can accurately predict if colon polyps are cancerous during a screening colonoscopy. Researchers compared the AI's predictions to the doctor's judgment and the final lab results. The goal is to see if AI c…

This trial tests whether a mild electrical stimulation device, applied near the wrist and ankle, can reduce pain during a colonoscopy performed without sedation. Sixty adults aged 18 to 75 will be randomly assigned to receive either real stimulation or a sham version. While the p…

This trial tests whether adding a ChatGPT-powered educational tool to standard instructions helps first-time colonoscopy patients achieve better bowel cleansing and feel less anxious before the procedure. Adults undergoing their first colonoscopy are randomly assigned to receive …

This study tested different sedation medications for colonoscopy to see which works best and is safest. 183 adults aged 18-60 received one of several sedation regimens given by non-anesthesia providers. The goal was to find the best balance of deep relaxation, quick onset, and fe…

This study tested whether watching videos with virtual reality glasses before a colonoscopy could lower patients' anxiety and steady their vital signs. Seventy adults were randomly assigned to use VR glasses or not. Researchers measured anxiety levels and blood pressure before th…

This study tested whether using a stress ball and listening to relaxing music during a colonoscopy can reduce pain and anxiety. 100 adults undergoing the procedure without sedation were split into two groups: one used the stress ball and music, the other received standard care. T…

This study tested if chewing gum or walking before a colonoscopy helps clean the bowel better and makes patients more satisfied. 168 adults were split into three groups: standard prep, gum chewing, or walking. The goal was to see if these simple activities improve the quality of …

This study looked at whether a doctor's encouraging words can help patients feel less pain and anxiety during a colonoscopy done without sedation. Over 100 adults took part, with some hearing positive phrases like "You're doing great" during the procedure. The goal was to see if …

This study tested whether listening to visualized meditation sessions for three days before a colonoscopy could help reduce anxiety, pain, and improve comfort. Seventy-two first-time colonoscopy patients participated. The meditation group listened to recordings twice daily before…

This study tested whether a smartphone app with video guidance helps patients prepare better for a colonoscopy compared to standard instructions. 488 adults were randomly assigned to use the app or receive usual education. The goal was to see if the app leads to cleaner bowels, m…

This study tested whether taking two bottles of a high-energy nutritional supplement (Resource® Energy Apricot) during colonoscopy bowel preparation could reduce hunger without harming the quality of the colon lining view. 299 adults scheduled for a colonoscopy took the supplemen…

This study measures the carbon dioxide emissions produced during colonoscopy for colorectal cancer screening, including energy use, equipment, medications, and waste. Researchers will also compare different polypectomy techniques to see which are more eco-friendly. The goal is to…

This study looked at 139 children having a colonoscopy to see how often the CMV virus is found in their gut tissue and blood. Some children had inflammatory bowel disease (Crohn's or colitis) and some did not. The goal was to learn which tests best detect CMV in the gut, helping …

This study looked at 164 adults aged 65 and older who had a colonoscopy with sedation. Researchers compared two common sedatives—propofol and dexmedetomidine—to see how they affected thinking and memory. They also checked whether frailty played a role. Participants took a simple …

This study looked at 1000 people getting a routine colonoscopy to see if the time of year affects how well the bowel is cleaned beforehand. Researchers compared bowel cleanliness across different seasons using a standard scoring system. The goal was to find out if seasonal change…

This study looked at 148 patients having a painless colonoscopy. Researchers used ultrasound to check when the stomach was empty after drinking a bowel-cleansing solution. They compared doing the colonoscopy within 2 hours versus waiting 2-4 hours after the stomach emptied. The g…

This study looked at 679 adults to find out what makes some people feel pain during a colonoscopy without sedation. The goal was to create a tool that predicts pain before the procedure, so doctors can take steps to make it more comfortable. By collecting basic health info and pa…