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Which sedation works best for colonoscopy? new study has answers

NCT ID NCT06763705

Symptom relief Sponsor: Qassim Health Cluster Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested different sedation medications for colonoscopy to see which works best and is safest. 183 adults aged 18-60 received one of several sedation regimens given by non-anesthesia providers. The goal was to find the best balance of deep relaxation, quick onset, and few side effects like low blood pressure or breathing problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

183 people

The number who actually took part.

Started

Jun 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Adults aged 18-60 years * Both Genders * Indication of colonoscopy procedure without advanced intervention * American Society of Anesthesiologists (ASA) physical status I or II * Competent to give informed consent * Exclusion criteria: * Personal history of allergic reaction or other contra-indications to midazolam, propofol or fentanyl * Age below 18 or above 60 years * Chronic use of benzodiazepines * ASA physical status III or above * Pregnancy * History of smoking or alcohol abuse * Body mass index \> 35 kg/m2 * History of airway obstruction or difficult intubation

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colonoscopy Conscious sedation Deep sedations

Contacts and locations

Locations

  • King Saud Hospital

    Unaizah, Al-Qassim Region, 56437, Saudi Arabia

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