CHRONIC OBSTRUCTIVE PULMONARY DISEASE

This study aimed to see if a salmon oil supplement called Cardio® could reduce inflammation and lower heart disease risk in people with chronic obstructive pulmonary disease (COPD). The trial planned to enroll adults with COPD who smoke or used to smoke. However, the study was wi…

This study tests an experimental drug called TQC2938 in 256 adults with moderate to severe COPD. The goal is to see if it can reduce the number of serious lung flare-ups over 24 weeks compared to a placebo. Participants will be randomly assigned to receive either the drug or a du…

This study compares a video telehealth pulmonary rehabilitation program to standard care for people hospitalized with a COPD flare-up. The goal is to see if the virtual program reduces hospital readmissions and improves breathing and quality of life. About 301 adults aged 40 and …

This study looks at the long-term safety of a drug called itepekimab for people with chronic obstructive pulmonary disease (COPD). About 700 adults who completed earlier itepekimab studies will receive the drug every 2 or 4 weeks for up to 52 weeks, followed by 20 weeks of monito…

This study tests an experimental drug called MK-5475 (frespaciguat) in adults who have both COPD and pulmonary hypertension (high blood pressure in the lungs). The main goal is to see if the drug helps people walk farther in 6 minutes after 24 weeks compared to a placebo. About 1…

This study tests an experimental drug called TQC2731 in 258 adults aged 40-80 with moderate to severe COPD. Participants receive either the drug or a placebo to see if it reduces the number of serious flare-ups over 24 weeks and improves breathing. The goal is to better control t…

This study tests whether TCM Daoyin therapy, a traditional Chinese movement and breathing practice, can improve lung function and exercise ability in 60 adults at risk for early-stage COPD. Participants will be randomly assigned to either Daoyin training or usual care. The goal i…

This study looks at whether adding an inhaled corticosteroid (ICS) for 4 weeks to the usual COPD treatment (LABA/LAMA) can improve how well the blood vessels in the lungs work. Researchers will measure blood vessel response in 30 adults with COPD, ages 40-80, who have smoked in t…

This study looks at two new types of pulmonary rehabilitation for people with COPD who cannot go to a hospital or clinic for the usual program. One option is telerehabilitation (using video calls and apps) and the other is a home-based program with nurse visits. The goal is to se…

This study looks at whether smokers with mild to moderate COPD who switch to e-cigarettes can reduce their symptoms and risk of flare-ups. About 30 participants will use e-cigarettes to cut down on regular cigarettes. Researchers will track lung function, walking distance, and sy…

This study was designed to track severe flare-ups (exacerbations) in people with COPD in Egypt, aiming to understand how often they happen and how they affect patients' health and healthcare use. It planned to look back at medical records from the previous three years. However, t…

This study is testing a wristband that monitors people with COPD at home. The goal is to see if it can catch sudden worsening of the disease (exacerbations) early. 64 adults with COPD who have had recent flare-ups will wear the device and be followed for several months.

This study looks at whether a new way of paying for healthcare, called bundled payments, improves quality and lowers costs. Researchers will analyze Medicare data from 440 provider organizations for common conditions like osteoarthritis and pneumonia. The goal is to see if this p…

This study follows nearly 3,000 people with COPD (a chronic lung disease) over several years to better understand how the disease progresses. Researchers measure lung function, mucus, and CT scans, and also look at how things like air pollution and home environment affect health.…

This study aimed to see if a computer program could predict how long patients would stay in a home hospital program. Researchers used data from past patients to train the program. The study was withdrawn before enrolling any participants, so no results are available.

This study aimed to see if a computer program could predict potassium levels in the blood using a simple heart monitor. Researchers planned to use data from patients treated at home. The study was withdrawn before any participants were enrolled, so no results are available.

This study looks at how tiny organisms in the lungs (airway microecology) are related to the development and changes of chronic obstructive pulmonary disease (COPD). Researchers will collect lung fluid from 210 adults with or at risk for COPD and track their lung function and sym…