CARDIOVASCULAR DISEASE

This study is testing whether a combination of advanced PET heart scans, intensive lifestyle coaching, and targeted medication is better at managing stable heart disease and preventing heart attacks than standard medical care. It involves about 1,085 adults aged 40 and older who …

This study is testing whether a probiotic supplement called Probacine can help protect patients' gut health and prevent organ problems after heart surgery. Researchers will enroll 500 adults undergoing cardiovascular surgery to see if the supplement improves recovery. The goal is…

This study is testing if giving a cholesterol-lowering drug called evolocumab very early to people hospitalized for a heart attack can help prevent future heart attacks, strokes, or death. It will compare giving the drug plus standard care against standard care alone in over 6,00…

This large study is testing whether a weekly injection called CagriSema can reduce serious heart problems like heart attacks and strokes in people who already have heart disease. About 7,100 participants aged 55+ with a history of heart issues will receive either the real injecti…

This study is testing a new oral medication called AZD0780 to see if it safely lowers 'bad' LDL cholesterol in adults who already have heart disease or are at high risk for it. About 3,000 participants will take either the new drug or a placebo (inactive pill) for one year, in ad…

This study is testing a simple, non-invasive method to check blood vessel health in aging Veterans. Researchers move a participant's leg gently while using an ultrasound to measure blood flow, which indicates how well the blood vessels are working. The goal is to see if this test…

This large study is testing whether taking daily vitamin D or fish oil supplements can prevent atrial fibrillation, a common type of irregular heartbeat, in healthy adults. It involves over 25,000 U.S. men and women who don't have a history of heart disease. Researchers are track…

This study is testing whether a personalized support program can help prevent early deaths in low-income adults. The program offers navigation help, personalized health plans, and compensation for health-related costs to reduce risks from heavy drinking, heart disease, and HIV. R…

This study is testing whether pharmacists can help people reduce their risk of heart disease. Over 1,000 adults with conditions like diabetes, high blood pressure, or obesity will work with pharmacists on lifestyle changes and medication management. The goal is to see if this pha…

This large study tested whether taking daily vitamin D or fish oil (omega-3) supplements could help prevent cancer, heart attacks, and strokes in healthy older adults. Over 25,000 U.S. men and women took either the real supplements or placebo pills for about five years. The main …

This study aims to understand if a person's genetic makeup influences how well omega-3 fish oil supplements improve heart disease risk factors like cholesterol and blood pressure. Researchers gave fish oil supplements to 200 healthy adults and measured changes in their blood. The…

This project is not a new treatment but a large-scale review of existing research. Researchers are analyzing data from many past diet studies to understand if replacing animal protein (like meat and dairy) with plant protein (like beans and nuts) improves health markers for condi…

This study aims to understand why African diaspora populations have higher rates of obesity, type 2 diabetes, and heart disease by examining their genetic makeup. Researchers will collect health information and blood samples from about 1,100 adults who identify as African America…

This long-term study follows a diverse group of 3,720 adults in Baltimore over many years. Its main goal is to understand why health differences exist between racial and income groups as people get older. Researchers use mobile medical vans and regular check-ups to collect health…

This large observational study follows over 10,000 adults in Paris for at least 10 years to understand how heart rate patterns, blood pressure regulation, and artery health affect cardiovascular disease risk. Participants undergo heart monitoring, ultrasound tests, and provide bl…

This study is tracking the long-term health of over 32,000 people who helped clean up the 2010 Deepwater Horizon oil spill or lived nearby. Researchers are comparing the health of workers who had direct exposure to oil and chemicals with those who did not, to understand if the sp…

This study aims to find better ways to detect heart blood flow problems in women who have chest pain symptoms but no major artery blockages. Researchers will compare results from a standard invasive angiogram test with a non-invasive MRI heart scan. The study will follow 375 wome…

This study aims to better understand the heart, lung, and mental health risks faced by people with rheumatoid arthritis. It will follow 4,000 participants for up to 10 years, using heart scans, lung tests, questionnaires, and blood samples. The goal is to learn how to spot these …

This long-running study is tracking over 1,500 Wisconsin adults to understand how sleep-disordered breathing develops and changes as people age. Researchers are checking in with the same group of people over decades to see how sleep problems might be linked to future heart, brain…

This study is testing whether people can reliably collect their own health data at home. Researchers want to see if methods like step counters, simple fitness tests, and questionnaires on a handheld device work well outside a clinic. The goal is to gather information to help desi…

This study aims to understand the long-term effects of ketogenic diets on heart health in adults with epilepsy. Researchers are measuring cholesterol, blood pressure, weight, and artery wall thickness over two years. The study includes adults already on the diet and those startin…