CARDIAC AMYLOIDOSIS

This study tests whether daily weight monitoring at home can help people with ATTR cardiac amyloidosis avoid hospital stays. The condition causes fluid buildup that leads to heart failure, and weight gain is an early warning sign. Participants will either use a remote scale with …

This study tests whether a special PET scan can detect blood clots inside the heart of people with cardiac amyloidosis and atrial fibrillation. Twenty participants will receive an injection of a tracer that binds to clots, then undergo a combined PET/MRI scan. The goal is to see …

This study is testing a new imaging agent called [18F]FT8 for PET/CT scans to see if it can safely and clearly show amyloid deposits in people with amyloidosis, a condition where abnormal proteins build up in organs. Researchers will compare the new scan with standard tests like …

This study tests whether a special PET scan using a radioactive tracer called [18F]Florbetaben can accurately diagnose cardiac AL amyloidosis, a rare condition where abnormal proteins build up in the heart. About 200 adults with suspected cardiac amyloidosis will receive one inje…

This study tests artificial intelligence (AI) tools that help doctors interpret heart ultrasound images more accurately and quickly. The goal is to see if AI can speed up the diagnosis of conditions like genetic heart muscle disease, blocked arteries, and cardiac amyloidosis. Up …

This study looks at whether increasing the heart rate using an existing pacemaker can improve heart failure symptoms and exercise ability in people with cardiac amyloidosis. Ten adults with a pacemaker and this heart condition will be monitored. The goal is to see if a simple pac…

This study looks at whether shiatsu, a type of Japanese bodywork, can improve symptoms and quality of life in people with severe cardiac amyloidosis. Researchers will compare targeted shiatsu to comfort shiatsu and no shiatsu. About 108 adults with this condition will take part, …

This study looks at men over 65 who have chest pain but no blocked arteries. Researchers want to find out how many of them have a hidden heart condition called cardiac amyloidosis. Participants will have blood tests, heart scans, and other exams. No treatment is given—this is onl…

This study looks at how often cardiac amyloidosis—a condition where abnormal protein builds up in the heart—occurs in people aged 80 and older who have been hospitalized for heart failure. Researchers will use bone scans to check for the disease in 637 participants. No treatments…

This study looks at tissue removed during back surgery to find people who may have a heart condition called transthyretin cardiac amyloidosis (ATTR-CA). The goal is to catch the disease early, when treatments work best. Researchers will test spine samples from 1,663 older adults …

This study is testing whether a special type of PET/MRI scan can predict serious heart events in people with cardiac amyloidosis, a condition where abnormal proteins build up in the heart. Researchers will scan 25 adults and then follow them to see who has a major heart problem l…

This study tests a new device that uses sound waves to measure stiffness in the heart and liver. Researchers want to see if it can help tell apart different types of heart failure. About 150 adults aged 60 and older with or without heart problems will take part. The goal is to im…

This study looks at whether the same amyloid deposits found in the brains of people with Alzheimer's disease can also build up in the heart and cause heart problems. Researchers will use special PET scans to check the hearts of 15 Alzheimer's patients who are already getting brai…

This study aims to improve how doctors diagnose and predict the course of rare heart muscle diseases (cardiomyopathies) using advanced MRI scans. Researchers will enroll 1000 people with suspected rare cardiomyopathies to test new imaging methods. The goal is to provide clearer, …

This study is testing how reproducible a special PET scan (using [18F]Florbetaben) is for detecting amyloid deposits in the heart. Researchers will scan 15 adults—some with cardiac amyloidosis and some without—twice to see if the results are consistent. The goal is to improve ima…