BORDERLINE PERSONALITY DISORDER
Clinical trials for BORDERLINE PERSONALITY DISORDER explained in plain language.
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Could a new pill ease borderline personality disorder?
Symptom relief CompletedThis study tested whether Caplyta (lumateperone) can reduce symptoms of borderline personality disorder (BPD) in adults. Sixty people with BPD received either Caplyta or a placebo for 8 weeks. The goal was to see if Caplyta leads to greater improvement in BPD symptoms compared to…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Symptom relief
Last updated May 26, 2026 07:41 UTC
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Phone app may ease daily stress for people with BPD traits
Symptom relief CompletedThis study tested whether a smartphone app called SAM (Stress Autism Mate) can help adults with borderline personality disorder (BPD) traits manage daily stress. Sixteen people used the app for four weeks while continuing their regular treatment. The app asked about their activit…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: GGZ Centraal • Aim: Symptom relief
Last updated May 26, 2026 07:34 UTC
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Magic mushroom compound shows promise for Tough-to-Treat depression and BPD
Symptom relief CompletedThis small study tested a single dose of psilocybin in 9 adults with both major depression and borderline personality disorder. Researchers measured changes in depression and BPD symptoms over time to see if the treatment was safe and helpful. The goal was to ease symptoms, not c…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Symptom relief
Last updated May 26, 2026 07:25 UTC
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Could a pill calm borderline personality disorder? new trial hints at hope
Symptom relief CompletedThis study tested a drug called vafidemstat in 211 adults with borderline personality disorder (BPD). The goal was to see if it could reduce symptoms like agitation and aggression over 14 weeks. Participants received either the drug or a placebo, and researchers measured changes …
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE2 • Sponsor: Oryzon Genomics S.A. • Aim: Symptom relief
Last updated May 26, 2026 07:24 UTC
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Can a 6-Month therapy cut Self-Harm as well as a Year-Long program?
Symptom relief CompletedThis study compares a 6-month version of dialectical behaviour therapy (DBT) to the standard 1-year program for people with borderline personality disorder who repeatedly self-harm. Researchers want to see if the shorter treatment is just as good at reducing self-harm and is more…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Centre for Addiction and Mental Health • Aim: Symptom relief
Last updated May 20, 2026 11:55 UTC
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Brain training boosts happy memories to fight borderline personality disorder
Symptom relief CompletedThis study tested a new way to help people with borderline personality disorder (BPD) by training their brain to respond more strongly to positive memories. 30 adults with BPD used real-time brain scans to learn how to increase activity in the amygdala, a brain area linked to emo…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Kymberly Young • Aim: Symptom relief
Last updated May 11, 2026 20:49 UTC
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Smartphone study tests if education eases BPD symptoms
Knowledge-focused CompletedThis study involved 83 adults recently diagnosed with borderline personality disorder (BPD). Participants watched educational videos about BPD or other topics and completed daily surveys about their emotions and social interactions. The goal was to see if learning more about BPD …
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated May 18, 2026 12:06 UTC
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Tiny study asks: does MBT work for Over-60s?
Knowledge-focused CompletedThis study looked at whether Mentalization-Based Therapy (MBT) helps people aged 60 and older who struggle in relationships. Three participants received MBT, and researchers used interviews and questionnaires to see if it improved their mental health and ability to understand oth…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Sponsor: University of Nottingham • Aim: Knowledge-focused
Last updated May 18, 2026 12:00 UTC