BORDERLINE PERSONALITY DISORDER
Clinical trials for BORDERLINE PERSONALITY DISORDER explained in plain language.
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Couple therapy shows promise for borderline personality disorder in new trial
Disease control Recruiting nowThis study tests a new therapy called Sage for couples where one partner has borderline personality disorder (BPD). The therapy aims to reduce BPD symptoms, improve relationship conflict, and support the mental health of both partners. Up to 152 couples will be randomly assigned …
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE2 • Sponsor: York University • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Eye movement therapy may calm emotional storms in borderline personality disorder
Symptom relief Recruiting nowThis study is testing whether a therapy called EMDR, which is known for treating PTSD, can also help people with borderline personality disorder (BPD). The goal is to see if EMDR can improve emotional control and reduce core BPD symptoms. The study will involve 56 adults with BPD…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia • Aim: Symptom relief
Last updated May 26, 2026 06:15 UTC
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Brain zaps for BPD: new study tests magnetic therapy
Symptom relief Recruiting nowThis study tests whether a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) can reduce symptoms of borderline personality disorder (BPD). Up to 30 adults with BPD will be randomly assigned to receive either real or sham (placebo) stimulation…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Symptom relief
Last updated May 26, 2026 06:11 UTC
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Brain training shows promise for borderline personality disorder
Symptom relief Recruiting nowThis study tests a brain-training technique called neurofeedback for people with borderline personality disorder (BPD) who struggle with intense, unstable emotions. The goal is to see if learning to calm a specific brain area (the amygdala) can reduce emotional ups and downs. 164…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE1, PHASE2 • Sponsor: Central Institute of Mental Health, Mannheim • Aim: Symptom relief
Last updated May 26, 2026 06:10 UTC
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Brain training shows promise for borderline personality disorder
Symptom relief Recruiting nowThis study tests a new type of mental training for people with borderline personality disorder (BPD). The training teaches a skill called 'reappraisal-by-distancing,' which helps people step back from strong emotions. Researchers want to see if this training changes brain activit…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Symptom relief
Last updated May 26, 2026 06:07 UTC
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Could MDMA help people with borderline personality disorder read emotions better?
Symptom relief Recruiting nowThis study looks at whether a single dose of MDMA can help adults with Borderline Personality Disorder feel more sociable and better recognize emotions in others. Ten participants will take MDMA and complete tasks measuring social thinking. The goal is to see if this drug can eas…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE2 • Sponsor: Yale University • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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Family support may boost BPD treatment outcomes
Symptom relief Recruiting nowThis study tests whether adding a case manager and family meetings to standard care helps people with borderline personality disorder function better and feel better. About 100 adults newly starting treatment will be randomly assigned to the new approach or usual care. The goal i…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: University Hospital Bispebjerg and Frederiksberg • Aim: Symptom relief
Last updated May 22, 2026 14:01 UTC
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New 10-Week therapy shows promise for taming BPD impulsivity in young adults
Symptom relief Recruiting nowThis study tests a 10-week therapy program called SINTYA for young adults aged 16-25 with borderline personality disorder (BPD). The program combines group and individual sessions to help reduce impulsive behaviors and improve emotional control. Researchers will compare impulsivi…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Symptom relief
Last updated May 18, 2026 12:00 UTC
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Video-Based therapy shows promise for teens with borderline symptoms
Symptom relief Recruiting nowThis study tests a group therapy called schema therapy that uses self-recorded videos to help teens with borderline symptoms. About 64 teens will be randomly assigned to either this therapy or standard care. The therapy includes 30 group sessions, 8 individual sessions, and paren…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Turku University Hospital • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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New drug BI 3031185 tested for safety in BPD and ADHD patients
Symptom relief Recruiting nowThis study is testing a new medicine called BI 3031185 in adults with borderline personality disorder (BPD) or attention-deficit/hyperactivity disorder (ADHD). The main goal is to see how safe and tolerable the drug is when given as a single dose. Participants are randomly assign…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: PHASE1 • Sponsor: Boehringer Ingelheim • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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Tailored emotion training may ease depression and anxiety
Knowledge-focused Recruiting nowThis study explores whether teaching people emotion regulation skills tailored to their individual needs works better than a one-size-fits-all approach. Researchers will enroll 390 adults with emotional difficulties, including depression, anxiety, and PTSD. Participants will lear…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Matthew Southward, PhD • Aim: Knowledge-focused
Last updated May 26, 2026 06:16 UTC
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Brain zaps + therapy: a new way to tame emotions?
Knowledge-focused Recruiting nowThis study tests whether a single session of brain stimulation (rTMS) combined with emotion regulation skills training can help people with mood, anxiety, or related disorders better control their emotions. About 240 adults aged 18-55 who struggle with emotion regulation will be …
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 26, 2026 06:15 UTC
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Brain zapping study aims to sharpen minds across multiple disorders
Knowledge-focused Recruiting nowThis study is testing whether a non-invasive brain stimulation technique called tDCS can improve executive functions—like memory, attention, and decision-making—in people with various neuropsychiatric conditions. Researchers will enroll 600 adults with diagnoses such as traumatic…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 13:52 UTC
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Shame may be a key warning sign for suicide in borderline personality disorder
Knowledge-focused Recruiting nowThis study looks at whether the tendency to feel shame can help predict suicide attempts in people with borderline personality disorder (BPD). Researchers will follow 688 adults with BPD for 5 years, tracking their shame levels and any suicide attempts. The goal is to better unde…
Matched conditions: BORDERLINE PERSONALITY DISORDER
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated May 19, 2026 11:48 UTC