Can couple therapy tame borderline personality disorder? new trial aims to find out
NCT ID NCT06458933
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new 12-session couple therapy called Sage for people with borderline personality disorder (BPD) and their partners. It aims to reduce BPD symptoms, improve relationship conflict, and support partner mental health better than standard individual therapy. Up to 152 couples will be randomly assigned to Sage or standard care and followed for six months after treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 304 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Mar 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
INCLUSION CRITERIA 1. Participant with borderline personality disorder (BPD) meets full diagnostic criteria for BPD (i.e., five or more BPD diagnostic criteria per the Diagnostic and Statistical Manual of Mental Disorders-5-TR) 2. Both members are at least 19-years-old 3. Both members consent to study participation 4. Both members consent to a member of the research team contacting one of their provided emergency contacts if there are imminent safety concerns. 5. Both members consent to having assessment interviews and treatment sessions audio- and video-recorded 6. Both members members reside in Ontario (with no plan to leave the province during the course of the study) 7. Both members members are fluent in English 8. Both members are willing to receive emails about the study 9. Both members have regular internet access from a private location for completion of study appointments EXCLUSION: 1. Severe intimate partner violence in their relationship in the past year (Endorsement of severe intimate partner violence items on Conflict Tactics Scale-2) 2. DSM-5 criteria A and B of schizophrenia, not better accounted for by BPD 3. Hospitalization in the past year for mania, or mania in the past three months 4. A substance/alcohol use disorder that is likely to require medical intervention (e.g., detoxification) to reduce use 5. A medical condition that is likely to require hospitalization within the next year 6. Scaled score below 70 on the Test of Premorbid Functioning, suggesting impaired intelligence and/or probable traumatic brain injury 7. Either participant in the dyad is not able to show proof of identification upon request at any point throughout the study or is not able to provide an accurate phone number or address upon request. 8. The individual with BPD is currently receiving an empirically-supported BPD treatment and is unwilling to pause the therapy for the duration of the active treatment phase
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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York University
RECRUITINGToronto, California, M3J1P3, Canada
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Other studies related to the condition(s) this trial covers.
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