BLADDER CANCER

This study tested a new drug, BI 907828, in adults with advanced cancers of the bile duct, pancreas, lung, or bladder that have a specific genetic change (MDM2 amplified, TP53 normal). Participants took a pill every three weeks. The trial was stopped early, but researchers were c…

This study tested a new drug called OC-001, either by itself or combined with avelumab (an immunotherapy), in people with advanced cancers that had spread. The goal was to check safety and how the drug moves through the body. The trial was stopped early, and only 73 people were e…

This study looked at how well the drug Adstiladrin works for people with bladder cancer when used in normal medical practice, not in a strict research setting. It included 202 adults who were prescribed the drug by their doctor. The main goal was to see if the cancer disappeared …

This study tested whether adding the drug trilaciclib to standard chemotherapy and maintenance therapy could help people with advanced bladder cancer live longer without their disease getting worse. The trial enrolled 92 adults with untreated, advanced or metastatic urothelial ca…

This study tested a drug called tovorafenib in people aged 12 and older with advanced solid tumors that have specific genetic changes (MAPK pathway). The goal was to see if the drug could shrink tumors. The study was stopped early, but the results may help guide future treatments…

This early-phase study tested a new drug called SO-C101, alone or with pembrolizumab, in 115 people with advanced solid tumors (like lung, kidney, or skin cancer) that stopped responding to standard treatments. The main goal was to check safety and find the right dose. The study …

This early-phase study tested a new medicine called PF-07921585, given alone or with another drug (sasanlimab), in adults with advanced solid tumors like lung, bladder, kidney, skin, head and neck, or colorectal cancer. The goal was to check safety and how the body handles the dr…

This study tested whether adding the immunotherapy drug avelumab to standard radiation therapy could help treat muscle-invasive bladder cancer in patients who cannot receive the chemotherapy drug cisplatin. The trial enrolled 14 participants and aimed to see if the combination co…

This study looked at whether a simple urine test measuring a protein called DEK could help doctors diagnose bladder cancer in people who have blood in their urine or pain when urinating. The test was compared to standard methods like cystoscopy and cytology. The trial was ended e…

This study tested a technique that helps people with advanced cancer and their partners organize traumatic memories and practice slow breathing to reduce PTSD symptoms. The approach aimed to shift how the brain processes trauma, moving from emotional reactions to more controlled …

This study looked at whether genetic changes found in urine can match those in tumor tissue for people with high-risk bladder cancer. The goal was to see if a urine test could help doctors choose the right immunotherapy without needing a tissue sample. The study was stopped early…