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Cancer drug trial ends early after safety check

NCT ID NCT03770494

First seen Nov 05, 2025 · Last updated Jun 17, 2026 · Updated 38 times

Summary

This early-stage study tested a new drug called LY3405105 in 54 people with advanced solid tumors. The main goal was to check the drug's safety and find the right dose. The study was stopped early, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Columbia University Medical Center

    New York, New York, 10032, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • Gustave Roussy

    Villejuif, 94805, France

  • Highlands Oncology Group

    Fayetteville, Arkansas, 72703, United States

  • Hospital Madrid Norte Sanchinarro

    Madrid, 28050, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Institut Bergonie

    Bordeaux, 33076, France

  • Institut Curie

    Paris, 75248, France

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • National Cheng-Kung Uni. Hosp.

    Tainan, 704, Taiwan

  • National Taiwan University Hospital

    Taipei, 10048, Taiwan

  • Princess Margaret Hospital

    Toronto, Ontario, M5TY 2M9, Canada

  • Smilow Cancer Hospital at Yale-New Haven

    New Haven, Connecticut, 06511, United States

  • Taichung Veterans General Hospital

    Taichung, 40705, Taiwan

  • Taipei Veterans General Hospital

    Taipei, 11217, Taiwan

  • University of Pennsylvania Hospital

    Philadelphia, Pennsylvania, 19104, United States

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

endometrial endometrioid adenocarcinoma epithelioid sarcoma neoplasm ovarian clear cell tumor ovarian endometrioid adenocarcinoma soft tissue sarcoma synovial sarcoma triple-negative breast carcinoma urinary bladder carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.