BLADDER CANCER

This early-stage trial is testing the safety of a new radioactive drug called ATO-101 for people with a specific type of bladder cancer that has come back after standard treatments. The drug is delivered directly into the bladder to try to destroy cancer cells while aiming to spa…

This study is testing if adding a very precise, high-dose radiation treatment helps people with bladder cancer that has spread to a few other places in the body. It will compare standard drug therapy alone to standard therapy plus this targeted radiation. The goal is to see if th…

This study is testing whether adding a drug called entinostat to standard chemotherapy can help control advanced bladder cancer that has stopped responding to initial treatment. It will involve about 29 patients whose cancer cannot be surgically removed and has spread. The main g…

This study is testing whether washing the bladder with two chemotherapy drugs, gemcitabine and docetaxel, can control high-risk bladder cancer that has stopped responding to the standard BCG treatment. The goal is to see if this approach can effectively treat the cancer and preve…

This study is testing whether a more personalized form of radiation therapy can reduce severe side effects for people with muscle-invasive bladder cancer. It will compare a new 'adaptive' technique, which adjusts the radiation daily based on bladder changes, against standard radi…

This study is for people with advanced bladder cancer that has continued to grow despite previous treatments. Researchers want to see if a new drug called sacituzumab tirumotecan helps patients live longer compared to standard non-platinum chemotherapy options. About 590 particip…

This early-stage study is testing a new cell-based treatment called SL-28 in adults with advanced solid tumors that have not responded to standard therapies. The main goals are to find the safest and most effective dose and to check for side effects. Participants will receive the…

This study is testing whether a daily pill called dutasteride can prevent low-grade bladder cancer from returning after initial surgery. It will involve 95 men and women who have had this type of cancer removed. The goal is to see if this simple, well-tolerated treatment can redu…

This study is testing a heated chemotherapy wash for the bladder in patients with high-risk bladder cancer that has not responded to standard treatments and who cannot have their bladder surgically removed. About 50 participants will receive the heated treatment weekly for six we…

This study tests whether a new care coordination program helps cancer patients better manage chronic conditions like high blood pressure, diabetes, and high cholesterol during cancer treatment. Researchers will compare patients who receive the new program to those getting usual c…

This study aims to see if two new diagnostic methods can better detect and stage bladder cancer. Researchers will test a special PET scan (called FAPI PET/CT) and two urine tests on 262 adults with suspected or confirmed bladder cancer. The goal is to compare these new methods ag…

This study aims to collect videos from a special blue light bladder scan procedure to train an artificial intelligence (AI) tool. The goal is to help doctors more accurately spot suspicious areas that could be bladder cancer during the scan. The research involves 500 adults who a…

This study aims to see if doctors can safely skip a routine urine test given before surgery to remove bladder tumors. Researchers want to know if not doing this test leads to the same low rate of post-surgery fevers and infections, while potentially reducing unnecessary antibioti…

This study aims to see if simple comfort measures can make routine bladder cancer procedures less stressful and painful. Researchers will test interventions like calming music, visual distractions, and optimized timing of numbing gel on 378 patients undergoing cystoscopy or bladd…

This study is testing whether a simple urine test can help doctors monitor prostate or bladder cancer without invasive procedures. Researchers will collect urine samples from 25 patients at different points during their standard cancer treatment to see if they can reliably detect…