BIPOLAR DISORDER (BD)

This study tests a noninvasive brain stimulation technique (temporal interference stimulation) in 70 people with stable bipolar disorder who also have obesity. The goal is to see if targeting a brain region that controls body rhythms can improve metabolism and weight. Participant…

This study is testing whether a 16-week ketogenic diet (low carbs, high fats, medium protein) is safe and helpful for teens and young adults (ages 12–21) with bipolar disorder who are experiencing depression or mixed episodes. Participants will continue their usual medications wh…

This study tests whether a nutrition program focused on healthy eating patterns can lower cardiovascular risk in 88 adults with bipolar disorder. Participants will either receive usual care or add dietary counseling sessions with a dietitian. The goal is to see if better food cho…

This study tests a new tool that combines a blood test with a questionnaire to help doctors correctly identify bipolar disorder in people who are currently depressed. About 623 adults with depression will give a blood sample and fill out forms. The goal is to see if this tool can…

This study tests whether a safe, non-invasive brain stimulation device (tDCS) used at home can reduce depressive symptoms in people with bipolar disorder. 212 adults with bipolar depression will receive either real or sham stimulation for 10 weeks. The goal is to see if this easy…

This study tests whether a three-week program combining a daily supplement (sodium butyrate) with virtual reality-based cognitive training can improve memory, attention, and other thinking skills in 160 middle-aged and older adults who have had depression or bipolar disorder but …

This study explores whether artificial intelligence can predict when someone with bipolar disorder might have a relapse. Researchers will collect data from 200 people with stable bipolar disorder and 200 healthy volunteers, analyzing their speech, facial expressions, text, eye mo…

This study looks at how people with conditions like schizophrenia, depression, bipolar disorder, Alzheimer's, Parkinson's, stroke, or epilepsy think and make decisions. Researchers will compare their performance on computer tasks to healthy volunteers. The goal is to create a det…

This small pilot study is testing a new program to help young adults (ages 18-35) recently diagnosed with bipolar disorder transition from hospital to community care. The program includes group education, one-on-one peer support, and help for community healthcare providers. The g…

This study is adapting a short questionnaire called the Hypomanic Personality Scale (HPS-6) for use with Romanian speakers. The goal is to see if this 6-question tool can reliably identify adults who may be at higher risk for bipolar disorder. Researchers will enroll 50 people ag…

This study will collect genetic samples and health information from 50,000 people with serious mental illnesses like bipolar disorder, schizophrenia, major depression, and dementia. Researchers will link this data to electronic health records to find patterns that could lead to b…

This study will follow 1,000 teenagers hospitalized for depression or bipolar disorder. Researchers will collect blood samples, brain scans, wearable device data, and psychological tests to find patterns that predict how well a teen responds to treatment. The goal is to better un…

This study aims to see how consistently people with bipolar disorder take their lithium medication in real life. About 50 participants will use a special pillbox that records the time they take their pill each day for 4 weeks. Researchers will also call them weekly to compare wha…

This study looks at how well people with schizophrenia or bipolar disorder can exercise and breathe. Researchers will measure lung function, breathing muscle strength, and quality of life in 150 adults aged 18 to 65. The goal is to find physical limits and help create better exer…