AVASCULAR NECROSIS

This study tests a procedure for people with early-stage osteonecrosis (bone death) of the hip. Doctors drill into the hip bone, inject a concentrated sample of the patient's own bone marrow, and add a special bone graft material called Genex. The goal is to see if this helps bon…

This phase 3 trial tests whether a combination of pentoxifylline (a muscle pain drug) and vitamin E can help heal jaw bone damage caused by osteoporosis or cancer treatments. About 100 people with medication-related jaw bone death will receive either the drug combo plus standard …

This study is testing a new modular shoulder replacement system in 105 people who need complex revision surgery due to joint disease, trauma, or cancer. The device can replace part or all of the upper arm bone. Researchers are tracking how long the implant lasts and how well pati…

This study is following 110 people who received a Tornier HRS shoulder replacement to see how well it improves pain and function. Participants have conditions like arthritis, fractures, or rotator cuff tears. The goal is to collect long-term safety and performance data for regula…

This study looks at two different hip implant shells (the Trident II and the older Trident Hemi) to see if they hold in place equally well after hip replacement surgery. About 87 adults aged 40-75 who need a new hip will be tracked for up to 10 years using special X-ray technique…

This study follows 200 adults getting a shoulder replacement with the Zimmer Trabecular Metal Reverse Shoulder System. It aims to see how long the implant lasts and how well it relieves pain and improves movement in people with conditions like arthritis, fractures, or failed prio…

This study follows 100 people who need a hip replacement to see how long the MiniMAX hip stem lasts and how well it works. Participants receive the stem during surgery and are checked for implant survival and hip function using the Harris Hip Score. The goal is to confirm the ste…

This study follows 757 people who received the Persona Partial Knee system, a device that replaces only the damaged part of the knee. The goal is to see how well the implant works over time by measuring patient-reported function and quality of life. Participants are adults with k…

This study follows 100 people who received a specific knee replacement system (EVOLUTION® NitrX™) to check its safety and how well it works. Participants have knee arthritis, joint disease, or related conditions. The main goal is to measure knee function and symptoms using a pati…

This study looks at how well a new knee replacement system works for people with chronic knee pain from arthritis or other conditions. About 240 adults who need a total knee replacement will receive the implant and be followed over time. The main goal is to see if the implant imp…

This study looks at how well a special hip liner works over time in people getting a hip replacement. About 202 adults aged 18 to 80 with conditions like arthritis or hip fractures will take part. The main goal is to see if the liner stays in place and causes few side effects.

This study follows 200 adults who received the Medacta Shoulder System to treat shoulder problems like arthritis, fractures, or to replace a previous implant. Researchers are checking how long the implant lasts, how well the shoulder works, and any side effects. The goal is to co…

This study compares two types of total knee replacements: one that uses bone cement and one that doesn't. About 300 adults with knee pain from arthritis or other conditions will be followed for up to 5 years. The goal is to see which method provides better pain relief, function, …

This study follows 73 people aged 18-80 who received a shoulder implant (Anatomical Shoulder Domelock System) to treat severe shoulder pain from arthritis or other conditions. Researchers will check how well the implant works and how long it lasts over 10 years. The goal is to co…

This study looks at how well the Insignia Hip Stem works and how safe it is for people needing a total hip replacement. It includes 313 adults with conditions like hip arthritis or fractures. Researchers will check implant survival and hip function for up to 10 years after surger…

This study follows 200 people who receive a cementless knee replacement (GMK Sphere) to see how long the implant lasts and how well it works. Participants have severe knee damage from arthritis or other conditions. The goal is to monitor safety and performance in real-world use, …

This study looks at how well a new hip replacement system, called CATALYSTEM, works in 119 people who need a total hip replacement due to conditions like arthritis or bone damage. The main goal is to see if the implant stays in place without problems for at least 2 years. Researc…

This study tracks 194 people who received the Comprehensive Nano shoulder system for conditions like arthritis or joint damage. Researchers will monitor how long the device lasts and how well the shoulder functions over 10 years. The goal is to gather real-world data to meet regu…

This study gathers information from 160 people who received a shoulder implant to see how long the implant lasts and how safe it is. Participants have conditions like arthritis or fractures. The goal is to use this data to make better implants and help doctors and patients make i…

This study is following 230 adults who received a G7 hip replacement system to see how long the implant lasts and how well it works. Participants have hip problems like arthritis or bone death. The study does not test a new treatment but simply watches and records outcomes over t…

This study follows 200 adults who received the Medacta Shoulder System to treat various shoulder issues like arthritis, fractures, or rotator cuff problems. The main goal is to see how long the implant lasts and how well the shoulder works after surgery. It is a post-market check…

This study follows 76 people who received a pyrocarbon shoulder implant to see how well it works and holds up over 5 to 10 years. Researchers measure shoulder pain, function, and any complications. The goal is to confirm the implant is safe and effective for long-term use.