APICAL PERIODONTITIS
Clinical trials for APICAL PERIODONTITIS explained in plain language.
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Laser zaps tooth infection better than sonic cleaning?
Disease control OngoingThis study compares two ways to clean infected root canals during a single dental visit: laser-activated irrigation versus sonic-activated irrigation. Sixty adults with chronic tooth infections needing a root canal revision will be randomly assigned to one method. Researchers wil…
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: University of Zagreb • Aim: Disease control
Last updated May 26, 2026 07:04 UTC
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Which root canal filler hurts less? new study compares two materials
Symptom relief OngoingThis study looks at 64 adults with infected tooth roots who need root canal treatment. Researchers are comparing two different sealing materials to see which one causes less pain and helps the bone heal better. Participants record their pain levels for a week and get X-rays to tr…
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: Ankara Yildirim Beyazıt University • Aim: Symptom relief
Last updated May 26, 2026 07:12 UTC
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Could a common antioxidant make root canals less painful?
Symptom relief OngoingThis study tests whether adding N-acetylcysteine (NAC) to standard root canal treatment reduces pain and improves healing in people with infected teeth and bone loss. Forty adults with dead teeth and signs of infection around the root tip will receive either NAC or standard medic…
Matched conditions: APICAL PERIODONTITIS
Phase: PHASE2 • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 22, 2026 13:52 UTC
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Which root canal filling hurts less? new study aims to find out
Symptom relief OngoingThis study looks at two different medicines placed inside a tooth during root canal treatment to see which one causes less pain and helps the infection heal better. Eighty adults with infected front teeth will receive one of the two medicines and report their pain levels over a w…
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: Ege University • Aim: Symptom relief
Last updated May 12, 2026 13:43 UTC
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Ozone vs. saline: which root canal rinse reduces stress better?
Knowledge-focused OngoingThis study looks at whether using ozone water during root canal treatment can affect oxidative stress markers in the fluid around the tooth root. Sixty adults with a single-rooted tooth infection (asymptomatic apical periodontitis) will be randomly assigned to receive either ozon…
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: KEZBAN MELTEM ÇOLAK • Aim: Knowledge-focused
Last updated May 26, 2026 07:01 UTC