ALZHEIMER'S DISEASE

This early-stage trial tests an oral biologic called Gut-X-001 in 120 people with Alzheimer's disease. The goal is to see if it can improve thinking, daily function, and brain health, while checking for safety. The study also looks at how the treatment affects gut bacteria and bl…

This early study tests whether a gentle ultrasound treatment can safely clear harmful debris from the brain in 15 adults who have signs of Alzheimer's risk but may not yet have symptoms. The approach uses low-intensity focused ultrasound, is noninvasive, and aims to improve brain…

This study tests an experimental drug called ABBV-1758 in about 210 adults with early Alzheimer's disease. The drug is given as an infusion or injection every 4 weeks for 24 weeks. Researchers will check for side effects and measure changes in brain amyloid plaques using PET scan…

This study tests if a safe, non-invasive treatment called rTMS (magnetic brain stimulation) can improve memory and thinking in people with mild to moderate Alzheimer's disease. Researchers think it may work by balancing the connection between gut bacteria and the brain. 200 Alzhe…

This study tests whether a trained peer mentor, along with personalized resource lists and text messages over 12 months, can reduce loneliness and help caregivers of people with dementia find end-of-life resources. About 330 caregivers will take part. The goal is to ease the burd…

This early-stage study tests the safety and tolerability of a new drug called AK152 in healthy volunteers and people with Alzheimer's disease. The trial will also measure how the drug moves through the body and whether it triggers an immune response. About 108 participants will t…

This study explores whether drinking beetroot juice twice a day is practical and safe for people with mild-to-moderate Alzheimer's disease. Thirty participants will take the juice for one week, with help from a caregiver. Researchers will check if it's easy to take, free of side …

This study tests whether a daily supplement called lithium orotate is safe and can reach the brain in people with early Alzheimer's. Forty adults will take either the supplement or a placebo for 9 weeks. Researchers will check for side effects, measure lithium levels in spinal fl…

This study aims to find out how many hospitalized patients in Iraq are malnourished, a problem that can lead to more complications and longer stays. Researchers will screen 300 adults admitted to medical, surgical, or neurology ICU wards using standard tools. The goal is to measu…

This study looks at whether a simple headband worn at home can measure sleep stages as accurately as a full sleep lab test in people with early or no Alzheimer's symptoms. About 35 participants will wear both devices at the same time in the lab for two nights, then use the headba…

This study looks at whether Ginkgo biloba, a common herbal supplement, can affect certain blood markers linked to Alzheimer's disease. Researchers will give either Ginkgo biloba or a placebo to 120 adults with mild memory problems for 6 months. They will measure changes in blood …

This study is testing a new set of tasks called the ExéSem battery to help doctors tell apart two types of language problems in people with Alzheimer's disease, vascular dementia, or primary progressive aphasia. The battery measures how well someone can name objects and understan…

This study will see if wearable devices like smartwatches and rings can catch early signs of memory loss and Alzheimer's disease. Researchers will track 150 adults aged 65 and older, comparing data from wearables with brain scans, blood tests, and thinking tests. The goal is to f…

This study tests a new tool that uses famous monuments to see if people with Alzheimer's have more trouble naming and identifying them than healthy older adults. Researchers will compare 220 participants aged 50 and older. The goal is to develop a simple screening test for early …

This study aims to adapt the widely used Mini-Mental State Examination (MMSE) memory test so it works better for people in Reunion Island. The current French version has questions that don't fit local culture, which can lead to wrong results. Researchers will test the new version…