ADVANCED CANCER

This study is for people with advanced biliary tract cancer whose disease is stable after initial chemotherapy and immunotherapy. It tests whether adding different drugs (lenvatinib, venadaparib, or IL-2) to maintenance immunotherapy can keep the cancer under control longer. Abou…

This study tests whether adding the experimental drug TST001 to standard chemotherapy and immunotherapy can help people with advanced stomach or gastroesophageal junction cancer live longer without their disease getting worse. About 820 adults with a specific tumor marker (Claudi…

This early-phase study tests a new drug, PF-07994525, in 120 adults with advanced multiple myeloma that has returned or not responded to treatment. The goal is to find a safe dose and see if the drug can shrink tumors. Researchers will closely monitor side effects and how the bod…

This early-stage study tests a new tablet called TQB3217 in 40 people with advanced solid tumors that have not responded to standard treatments. The main goals are to check the drug's safety, find the best dose, and see how the body processes it. This is a first-in-human trial, s…

This study tests whether a four-session death education program can help family caregivers of advanced cancer patients feel less anxious, depressed, and more at peace. About 30 caregivers will take part in one-on-one sessions over four weeks. The main goal is to see if the progra…

This study looks at whether two types of spiritual care can help people with advanced cancer feel better spiritually and use healthcare services differently. About 288 patients from religious communities will take part. Researchers will measure spiritual well-being, quality of li…

This study tests a program called ROCKS to help people with advanced cancer and their family caregivers talk about and plan for future medical care. About 152 patient-caregiver pairs will be randomly assigned to the program or usual care. The goal is to see if the program helps m…

This study tests a smartphone app called I-STAMP designed to help people with advanced cancer manage their pain and keep track of their medications. About 73 participants will use the app and then rate how easy it is to use and how helpful they find it. The goal is to see if the …

This study tests whether a special bone cement (made with bioactive glass) combined with ultrasound can safely stabilize bones and reduce pain in people with advanced cancer that has spread to the pelvis. Only 8 participants will receive the treatment alongside standard care, and…