Vaginitis

This study tests a new vaccine called Candi5V in 251 women who get frequent yeast infections (at least 3 per year). The vaccine is designed to train the body's immune system to fight Candida fungus. Researchers will check if it's safe and if it reduces future infections.

This trial tests whether transferring vaginal fluid from healthy donors can help people with recurrent bacterial vaginosis (BV) that doesn't respond well to antibiotics. Participants receive either the donor fluid or a placebo (saline) to see if the transplant restores a healthie…

This study tests whether transferring healthy vaginal bacteria from donors can cure recurrent bacterial vaginosis (BV). Ten women with frequent BV will receive the transplant. The goal is to restore natural balance and prevent repeat infections without antibiotics.

Researchers are comparing the SavvyCheck Vaginal Yeast Test, a rapid swab test women use themselves, against standard vaginal yeast culture done in a lab. The study enrolls women with symptoms such as vaginal itching, discharge, soreness, or burning. The goal is to measure how ac…

This study aimed to find out if checking pregnant women for bacterial vaginosis every two weeks could reduce the chance of early delivery. It planned to include women with a history of preterm birth. However, the trial was withdrawn before any participants were enrolled, so no re…

This early-stage study tests whether LCFA-01, a natural gel containing oleic acid, is safe and comfortable when placed in the vagina. Thirty healthy women aged 18-40 will use the gel and be monitored for side effects, discomfort, and how much of the product enters the bloodstream…

This phase 2 trial tests whether injecting platelet-rich plasma (PRP) into the vulva and vagina can improve symptoms of genitourinary syndrome of menopause (GSM) in breast cancer survivors. GSM causes dryness, burning, and pain, often worsened by cancer treatments. The study enro…

This study tests a product called pHyph for treating thrush (a vaginal yeast infection) in adult women. The goal is to see if pHyph reduces symptoms like itching, burning, and irritation. 48 women will either use pHyph daily for 6 days or receive no treatment, and researchers wil…

This study aimed to see if adding a hyaluronic acid-based vaginal moisturizer to standard vaginal estrogen therapy provides extra relief for menopause-related vaginal symptoms. It planned to enroll postmenopausal women aged 45 and older who had not used these treatments recently.…

This study tests a non-hormonal laser treatment for genitourinary syndrome of menopause (GSM) in women who have completed cancer treatment. GSM causes symptoms like vaginal dryness and pain, which can affect quality of life. The study will compare the laser therapy to a control g…

This study tests a gel called Hyalo Gyn® to see if it helps with vaginal dryness in women who have had breast cancer and are past menopause. About 156 women will use the gel or a placebo every three days for 12 weeks. The goal is to see if the gel reduces dryness and other sympto…

This study tests a device called INNEA AQUA, used in the vagina, to see if it safely reduces symptoms of vulvo-vaginal atrophy (VVA) in adult women. VVA can cause itching, soreness, and pain during sex. The trial compares the device to standard care in 62 women aged 18-75. Resear…

This study looks at two treatments for vaginal dryness in women with estrogen receptor-positive breast cancer who are taking aromatase inhibitors. One group uses a vaginal estrogen ring that releases a low dose of estrogen over 90 days, while the other uses a non-hormonal vaginal…

This study tests whether injecting platelet-rich plasma (PRP) — made from a woman's own blood — into the vaginal wall can improve sexual function and reduce dryness caused by menopause. Thirty postmenopausal women with genitourinary syndrome of menopause will receive either PRP o…

This study aims to understand why some women get recurrent vaginal yeast infections (vulvovaginal candidiasis) and others don't. Researchers will compare the vaginal microbiome, immune markers, and metabolic profiles of women with and without the infection. By identifying key dif…

This study looks at 120 Canadian women to understand why some get repeated yeast infections while others don't. Researchers will compare the vaginal yeast and bacteria of women with their first infection, those with recurrent infections, and those with yeast but no symptoms. Part…

This study in Nepal tests whether using rapid point-of-care tests for sexually transmitted infections can reduce the overuse of antibiotics for vaginal discharge. About 1,500 women will be split into three groups: standard care, test-guided treatment, or test-guided treatment plu…