Somatoform disorder

This trial tests whether fluoxetine, a common antidepressant, can improve bowel function in adults with chronic constipation that has not responded to standard laxatives. Participants also show features of somatic symptom disorder, where emotional distress appears as physical sym…

This trial tests whether combining brain stimulation with physical therapy can improve walking in adults with functional neurological disorder (FND), a condition where the brain's movement signals are disrupted. Participants receive either TMS-enhanced physical therapy or standar…

This study compares two behavioral programs for young women aged 14-22: a new one called Priorities, which helps build self-worth beyond weight and shape, and The Body Project, an established eating disorder prevention program. Researchers want to see which is more effective at r…

This trial tests whether a six-week self-guided psychological program can reduce symptoms of body dysmorphic disorder in adolescents aged 15 to 18. Participants with symptoms are split into two groups: one receives the program, the other does not. Researchers compare changes in b…

This trial asks whether adding structured exposure exercises to response prevention—a core part of exposure therapy—makes a meaningful difference for people who are highly bothered by persistent physical symptoms. About 360 adults with high symptom burden will be randomly assigne…

This study investigates whether adding a painless, non-invasive vagus nerve stimulation through the ear to standard physiotherapy can improve motor symptoms and quality of life in people with Functional Neurological Disorder (FND). Researchers will first compare brain function in…

This study looks at people with recent low back pain that might turn into long-term pain. It compares a two-week program with a team of specialists (like doctors, physiotherapists, and psychologists) to standard physiotherapy sessions over several weeks. The goal is to see which …

This study tests a mobile app designed for people with functional movement disorder (FMD), a condition where the brain doesn't send movement signals properly. The app lets users record symptoms, stress, and mood as they happen, and offers simple self-help tools. Ten adults with F…

This study tests whether very short (4 or 8 sessions) psychological treatments can reduce symptoms of anxiety, depression, and stress-related physical complaints. About 184 adults with mild to moderate symptoms will be randomly assigned to group or individual therapy, or a relaxa…

This study will survey 400 medical students at Sohag University in Egypt to understand how health anxiety impacts their quality of life. Participants will fill out two questionnaires: one measuring health anxiety and another assessing physical and mental well-being. The results c…

This study looks at whether people with relapsing-remitting multiple sclerosis (RRMS) can have a relapse—new or worsening symptoms—without any visible inflammation on an MRI scan. Researchers will follow 136 adults who are having a suspected relapse, performing early brain and sp…

This study will compare 250 children aged 6 to 18 with chronic skin diseases to 250 healthy children to see how common body dysmorphic disorder (BDD) is in each group. Researchers will use a simple questionnaire to spot BDD symptoms and another to measure how skin problems affect…

This study looks at how people with functional movement disorders (FMD) experience a sense of control over their actions. Researchers will measure how quickly participants respond when asked if they caused an action, using a computer task. The goal is to develop a more objective …