Pharyngitis

This phase 3 trial tests whether Jinhua Qinggan Granules, a traditional Chinese herbal medicine, can eliminate symptoms of acute upper respiratory infections (like fever, sore throat, and congestion) within three days. About 273 adults with early-stage cold or flu will receive ei…

This study tested a new rapid test called SPOTFIRE ST for people with sore throats in urgent care. The test uses PCR to find up to 13 different viruses and bacteria in about 20 minutes. Researchers wanted to see if doctors find it useful, how accurate it is, and whether patients …

This study tested whether a rapid molecular test using saliva can accurately diagnose strep throat in children aged 3-15. Researchers compared the saliva test to standard throat swab methods in 800 children visiting primary care. If accurate, this could replace uncomfortable thro…

This study tests whether a specially designed probiotic, Streptococcus salivarius eK12, can prevent repeated strep throat infections in children aged 3 to 10. The probiotic is given as a daily supplement and aims to crowd out the harmful bacteria without antibiotics. Researchers …

This study tested a small clip attached to the breathing tube used during anesthesia to see if it could prevent sore throat, voice changes, and trouble swallowing after surgery. 100 adults having surgery with general anesthesia took part. The clip is designed to reduce pressure o…

This trial tests whether a spray made from lavender and ginger oils can ease sore throat, thirst, and nausea after kidney stone surgery. About 110 adults who have the surgery under general anesthesia will receive the aromatic spray, a placebo, or standard care. Researchers will m…

This study compared two types of breathing tubes (Air-Q and Proseal LMA) in 97 elderly patients aged 65-90 undergoing surgery. The goal was to see which device works better and causes fewer side effects like sore throat. Researchers measured how well each tube sealed the airway a…

This study tested whether placing a throat pack soaked in the steroid dexamethasone could reduce sore throat after septoplasty (nose surgery). 65 adults were randomly assigned to receive either a dexamethasone-soaked pack, a saline-soaked pack (placebo), or no pack. The main goal…

This study tested whether using a pre-inflated tracheal tube cuff during intubation reduces sore throat after surgery. 250 adults with non-difficult airways were randomly assigned to either the pre-inflated cuff method or the standard deflated cuff method. The goal was to see if …

This study looked at whether giving patients menthol ice or frozen saline after lumbar disc surgery could reduce thirst and sore throat. 102 adults who had surgery under general anesthesia took part. The researchers measured thirst discomfort and throat pain to see if these simpl…

This study tested whether adding dexmedetomidine or alkalinized lidocaine to the breathing tube cuff could prevent sore throat after long surgery where patients lie face down. Only 4 adults having spine surgery took part. Researchers checked for sore throat, hoarseness, and cough…

This study tested whether putting the breathing tube (endotracheal tube) in the fridge before use could reduce sore throat after surgery. 116 adults having elective surgery took part. The researchers measured how many people had a sore throat and how bad it was in the hours after…

This completed study looked at 289 children to understand what factors increase the risk of serious complications from pharyngitis (sore throat), such as abscesses or severe neck infections. Researchers compared children hospitalized for these complications with those who had pha…

This completed early-phase study tested a new way to study Strep A bacteria, which causes strep throat and can lead to serious heart disease. Researchers safely exposed 40 healthy adults aged 18-40 to a specific strain of Strep A under controlled conditions. The goal was to see h…

This study looked at 53 adults having ear surgery (tympanoplasty) with their head turned to the side. Doctors used ultrasound to measure the optic nerve sheath diameter, which can indicate pressure inside the skull. The goal was to see if the sideways head position changes that p…

This study tested a program to help doctors prescribe antibiotics more appropriately for common childhood infections like earaches, sore throats, and sinusitis. Over 1,000 doctors took part, receiving online training, personalized feedback on their prescribing habits, and support…

This study looked at 337 adults who had laparoscopic surgery with a breathing tube. Researchers measured how long the tube's cuff pressure was too high and checked if that led to a sore throat after surgery. The goal was to see if there is a link between cuff overpressure and sor…

This study tested whether giving doctors automated reports on their antibiotic prescribing habits could improve how often they follow official guidelines. Researchers looked at over 26,000 patients with pneumonia, ear infections, or sore throat. They compared antibiotic use befor…