Could a medicated throat pack ease pain after nose surgery?
NCT ID NCT07486544
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether placing a throat pack soaked in the steroid dexamethasone could reduce sore throat after septoplasty (nose surgery). 65 adults were randomly assigned to receive either a dexamethasone-soaked pack, a saline-soaked pack (placebo), or no pack. The main goal was to measure sore throat severity in the first 24 hours after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dexamethasone
- What this could lead to
- If it works, this could offer a simple way to reduce sore throat after nasal surgery, making recovery more comfortable.
- What could go wrong
- This is a small, single-center trial with 65 patients, so results may not apply to everyone. Dexamethasone may also have side effects like increased infection risk.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
-
65 people
The number who actually took part.
- Started
-
Mar 2026
- Finished
-
Apr 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 65 years, * Both male and female, * Classified as American Society of Anesthesiologists (ASA) physical status I to III, and * Scheduled for elective septoplasty. Exclusion Criteria: * Preoperative sore throat, * Recent upper respiratory infections, * Anticipated difficult airway, * Existing digestive, respiratory, or cervical conditions, * Regular smoking, * Steroid use within 48 hours prior to surgery, and * Pregnancy. * Patients on chronic corticosteroid therapy, antitussives, or antihypertensive medications * With known effects on airway reactivity or bleeding risk, * Those with uncontrolled hypertension, or * With known allergies to any of the study medications or their components
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Assiut University
Asyut, 71511, Egypt
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Other studies related to the condition(s) this trial covers.
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