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Ice cream or spray: which soothes Post-Thyroidectomy pain better?

NCT ID NCT07531147

Symptom relief Sponsor: Izmir Katip Celebi University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a flurbiprofen spray or ice cream can reduce throat pain and improve voice quality after thyroid removal. One hundred adults having thyroid surgery will receive either the spray, ice cream, or a placebo spray five hours after their operation. Researchers will then measure pain levels and voice quality to see which option works best.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
flurbiprofen spray and ice cream
What this could lead to
If effective, this could offer simple, low-cost options for managing post-thyroidectomy throat pain and voice issues.
What could go wrong
This is a small, early-phase trial with only 100 participants, so results may not apply broadly. The interventions are tested only once at 5 hours after surgery, limiting conclusions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * No history of neck surgery * Age between 18-85 years * Undergoing thyroidectomy * Agreeing to participate in the study * Operation duration between 60-120 minutes Exclusion Criteria: * History of neck surgery * History of radiotherapy to the head and neck region * Pre-operative or post-operative vocal cord paralysis * Pre-operative phonetic disorder * Pre-operative laryngeal pathology * Being under 18 years of age * Refusal to participate in the study * Smoking * Flurbiprofen allergy * Lactose intolerance

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Conditions

The condition(s) this trial relates to.

pharyngitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sore throat Thyroidectomy Voice quality

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Izmir Katip Celebi University

    Izmir, 35620, Turkey (Türkiye)

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