Pharyngitis

This early-stage study tests a new imaging agent called 18F-4FN for PET scans to safely detect inflammation in the body. It involves 55 adults with cancer who are on immunotherapy or have suspected inflammation. The goal is to see if this agent can highlight areas of inflammation…

This study tests a new device that uses artificial intelligence to help diagnose ear infections, strep throat, and asthma flare-ups in children. About 84 kids aged 3 to 17 will either use the device at home with a doctor's video visit or receive standard in-person care. The goal …

This study is testing an oral spray called OROSEDAL to see if it helps relieve pain from sore throats, canker sores, and other minor mouth lesions. About 124 children and adults will use the spray as prescribed and report their pain levels over 6 days. The spray works by forming …

This study tests whether using a smaller breathing tube during thyroid surgery can lower the chance of a sore throat afterward. 180 women having thyroid surgery will be randomly assigned to receive a tube with an inner diameter of 6.0, 6.5, or 7.0 millimeters. Researchers will ch…

This study tests two throat sprays (CDN and CW) for adults with a cough from a viral cold. About 58 people will use one of the sprays for 7 days and report how well it works and any side effects. The goal is to see if these sprays are safe and help ease cough symptoms.

This study tests two simple, low-cost methods—chewing sugar-free gum or gargling cold water—before a bronchoscopy to see if they reduce sore throat and swallowing difficulty afterward. About 100 adults scheduled for diagnostic bronchoscopy will be randomly assigned to one of thes…

This study tests whether Jing Si herbal tea liquid packets can ease symptoms of chronic pharyngitis (long-term sore throat). About 120 adults with chronic pharyngitis will drink either the herbal tea or a placebo for a period. Researchers will measure changes in throat discomfort…

This study looks at whether not suctioning the breathing tube before removing it is safe and might reduce coughing and sore throat. About 408 adults having planned surgery will be randomly assigned to either routine suctioning or no suctioning. The main goal is to see if oxygen l…

This study aims to see if analyzing the chemicals in a child's breath can help diagnose and monitor diseases like asthma, neurological disorders, and type 1 diabetes. Researchers will collect breath samples from up to 3,600 children and teens to find patterns linked to these cond…

This study aims to learn more about PFAPA, a condition that causes repeated fevers, sore throats, and mouth sores in children. Researchers will collect blood, saliva, stool, and tonsil tissue from 1,500 people with PFAPA or other tonsil problems. No treatment is given; the goal i…

This pilot study is measuring prednisolone levels in 120 people with inflammatory diseases like thyroid eye disease, vasculitis, COPD, asthma, and others. Participants take high-dose prednisolone as part of their routine care, and researchers take timed blood samples to see how t…

This study tests whether having nurses or pharmacists, instead of doctors, do the first assessment for a sore throat can reduce unnecessary antibiotic use. Researchers will compare how often each type of health professional follows official guidelines. The goal is to see if chang…

This study looks at 320 adults who are about to start strong immune-suppressing therapy and have already had at least two COVID-19 shots. Researchers want to find out if giving a COVID-19 booster right before starting therapy or waiting six months provides better protection. Part…

This study looks at children ages 5 to 15 who test positive for strep throat to understand why some become carriers—meaning they have the bacteria but no symptoms. Researchers will collect throat samples and analyze gene activity to compare carriers with those who have active inf…

This study looks at how families feel about antibiotic use and whether a Garmin smartwatch can track symptoms in children aged 4-17 with common infections like UTIs, tonsillitis, or skin infections. About 300 children from the Royal Children's Hospital Emergency Department will w…