Peripheral neuropathy
MONDO:0005244A disorder affecting the peripheral nervous system. It manifests with pain, tingling, numbness, and muscle weakness. It may be the result of physical injury, toxic substances, viral diseases, diabetes, renal failure, cancer, and drugs.
Also known as: neuropathy, peripheral nerve disorder, peripheral neuropathy
1469 clinical trials for this condition and its sub-types, 93 tagged with Peripheral neuropathy itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Peripheral neuropathy
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Hereditary peripheral neuropathy 6 trials · 478 incl. sub-types
65 sub-types
- Carpal tunnel syndrome 165 trials Sub-types →
- Charcot-Marie-Tooth disease 51 trials · 77 incl. sub-types Sub-types →
- Familial amyloid neuropathy 52 trials · 54 incl. sub-types Sub-types →
- Hereditary sensory and autonomic neuropathy 52 trials · 54 incl. sub-types Sub-types →
- Proximal spinal muscular atrophy 14 trials · 42 incl. sub-types Sub-types →
- Metachromatic leukodystrophy 20 trials Sub-types →
- Krabbe disease 15 trials Sub-types →
- Sandhoff disease 13 trials Sub-types →
- Tay-Sachs disease 13 trials Sub-types →
- Chediak-Higashi syndrome 9 trials
- Leigh syndrome 9 trials Sub-types →
- Peroxisome biogenesis disorder 4 trials · 8 incl. sub-types Sub-types →
- Adrenomyeloneuropathy 7 trials
- Cerebrotendinous xanthomatosis 6 trials
- Kearns-Sayre syndrome 5 trials
- Distal hereditary motor neuropathy 0 trials · 4 incl. sub-types Sub-types →
- Hereditary neuropathy with liability to pressure palsies 4 trials
- Mitochondrial neurogastrointestinal encephalomyopathy 4 trials Sub-types →
- Ornithine aminotransferase deficiency 4 trials
- Pyruvate dehydrogenase deficiency 2 trials · 4 incl. sub-types Sub-types →
- NARP syndrome 3 trials
- Biotinidase deficiency 3 trials
- Coenzyme Q10 deficiency 3 trials Sub-types →
- Giant axonal neuropathy 2 trials · 3 incl. sub-types Sub-types →
- Hereditary motor and sensory neuropathy 3 trials Sub-types →
- Methylmalonic aciduria and homocystinuria type cblC 3 trials
- Mitochondrial DNA depletion syndrome 4a 3 trials
- Abetalipoproteinemia 2 trials
- Fumaric aciduria 2 trials
- Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2 2 trials
- Niemann-Pick disease type B 1 trial
- PRPS1 deficiency disorder 1 trial
- Adult polyglucosan body disease 1 trial
- Familial isolated deficiency of vitamin E 1 trial
- Homocystinuria due to methylene tetrahydrofolate reductase deficiency 1 trial
- Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency 1 trial
- Neuropathy, congenital hypomelinating 0 trials · 1 incl. sub-types Sub-types →
- Sensory ataxic neuropathy, dysarthria, and ophthalmoparesis 1 trial Sub-types →
- Charcot-Marie-Tooth disease type 5 0 trials
- EMILIN-1-related connective tissue disease 0 trials
- Finnish type amyloidosis 0 trials
- PHARC syndrome 0 trials
- VPS13A-related neurodegenerative disease 0 trials
- Amyotrophic neuralgia 0 trials
- Ataxia - oculomotor apraxia type 4 0 trials
- Attenuated Chédiak-Higashi syndrome 0 trials
- Beta-mannosidosis 0 trials
- Cataract-growth hormone deficiency-sensory neuropathy-sensorineural hearing loss-skeletal dysplasia syndrome 0 trials
- Congenital trigeminal anesthesia 0 trials
- Familial episodic pain syndrome 0 trials Sub-types →
- Familial recurrent peripheral facial palsy 0 trials
- Hereditary motor and sensory neuropathy, Okinawa type 0 trials Sub-types →
- Hereditary sensory and autonomic neuropathy with spastic paraplegia 0 trials
- Infantile axonal neuropathy 0 trials
- Meralgia paraesthetica, familial 0 trials
- Neurodegeneration with brain iron accumulation 2A 0 trials
- Neuropathy with hearing impairment 0 trials
- Neuropathy, hereditary sensory and autonomic, type IId 0 trials
- Non-progressive predominantly posterior cavitating leukoencephalopathy with peripheral neuropathy 0 trials
- Optic atrophy-ataxia-peripheral neuropathy-global developmental delay syndrome 0 trials
- Oxoglutaricaciduria 0 trials
- Peripheral motor neuropathy, childhood-onset, biotin-responsive 0 trials
- Primary CD59 deficiency 0 trials
- Progressive demyelinating neuropathy with bilateral striatal necrosis 0 trials
- Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1 0 trials
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Neuralgia 238 trials · 383 incl. sub-types
5 sub-types
- Sciatica 46 trials · 68 incl. sub-types Sub-types →
- Cranial neuralgia 0 trials · 53 incl. sub-types Sub-types →
- Post-infectious neuralgia 0 trials · 33 incl. sub-types Sub-types →
- Pudendal neuralgia 9 trials
- Familial episodic pain syndrome 0 trials Sub-types →
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Nerve compression syndrome 24 trials · 207 incl. sub-types
3 sub-types
- Carpal tunnel syndrome 165 trials Sub-types →
- Piriformis syndrome 25 trials
- Meralgia paresthetica 5 trials Sub-types →
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Diabetic neuropathy 181 trials · 192 incl. sub-types
2 sub-types
- Diabetic polyneuropathy 50 trials
- Diabetic autonomic neuropathy 7 trials
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Chemotherapy-induced neuropathy 171 trials
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Polyneuropathy 32 trials · 132 incl. sub-types
10 sub-types
- Polyradiculoneuropathy 1 trial · 64 incl. sub-types Sub-types →
- Chronic polyneuropathy 0 trials · 62 incl. sub-types Sub-types →
- Demyelinating polyneuropathy 2 trials · 62 incl. sub-types Sub-types →
- Critical illness polyneuropathy 39 trials
- Polyneuritis 3 trials
- Toxic polyneuropathy 1 trial · 3 incl. sub-types Sub-types →
- Idiopathic progressive polyneuropathy 0 trials
- Organophosphate-induced delayed polyneuropathy 0 trials
- Paraneoplastic polyneuropathy 0 trials
- Polyneuropathy in collagen vascular disease 0 trials
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Mononeuropathy 4 trials · 111 incl. sub-types
7 sub-types
- Sciatic neuropathy 9 trials · 72 incl. sub-types Sub-types →
- Ulnar neuropathy 7 trials · 21 incl. sub-types Sub-types →
- Peroneal neuropathy 9 trials
- Femoral neuropathy 7 trials
- Radial neuropathy 1 trial Sub-types →
- Tibial neuropathy 0 trials · 1 incl. sub-types Sub-types →
- Mononeuritis simplex 0 trials Sub-types →
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Acquired peripheral neuropathy 0 trials · 95 incl. sub-types
12 sub-types
- Cranial neuralgia 0 trials · 53 incl. sub-types Sub-types →
- Multifocal motor neuropathy 9 trials
- Pudendal neuralgia 9 trials
- POEMS syndrome 8 trials
- Polyneuropathy associated with IgM monoclonal gammapathy with anti-MAG 8 trials
- Non-recovering obstetric brachial plexus lesion 6 trials
- Anterior cutaneous nerve entrapment syndrome 2 trials
- Radiation-induced plexopathy 1 trial
- CANOMAD syndrome 0 trials
- Axonal polyneuropathy associated with IgG/IgM/IgA monoclonal gammopathy 0 trials
- Neuralgic amyotrophy 0 trials
- Simple cryoglobulinemia 0 trials
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Nerve plexus disorder 0 trials · 75 incl. sub-types
4 sub-types
- Brachial plexus neuropathy 13 trials · 72 incl. sub-types Sub-types →
- Lumbosacral plexus lesion 0 trials · 2 incl. sub-types Sub-types →
- Radiation-induced plexopathy 1 trial
- Nerve plexus neoplasm 0 trials Sub-types →
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Sensory peripheral neuropathy 4 trials · 58 incl. sub-types
1 sub-type
- Hereditary sensory and autonomic neuropathy 52 trials · 54 incl. sub-types Sub-types →
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Traumatic neuropathy 55 trials
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Neuritis 18 trials · 29 incl. sub-types
7 sub-types
- Vestibular neuronitis 9 trials
- Polyneuritis 3 trials
- Brachial plexus neuritis 0 trials Sub-types →
- Mononeuritis simplex 0 trials Sub-types →
- Motor nerve neuritis 0 trials Sub-types →
- Neuritis of upper limb 0 trials Sub-types →
- Neuroretinitis 0 trials
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Peripheral nerve lesion 1 trial · 12 incl. sub-types
4 sub-types
- Femoral neuropathy 7 trials
- Lesion of sciatic nerve 2 trials Sub-types →
- Ulnar nerve lesion 2 trials
- Radial nerve lesion 0 trials
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Autonomic neuropathy 7 trials · 10 incl. sub-types
2 sub-types
- Diabetic autonomic neuropathy 7 trials
- Horner syndrome 0 trials Sub-types →
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Chronic idiopathic neuropathy 5 trials
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Neuropathy, small fiber 4 trials
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Axonal neuropathy 1 trial · 4 incl. sub-types
3 sub-types
- Giant axonal neuropathy 2 trials · 3 incl. sub-types Sub-types →
- Congenital axonal neuropathy with encephalopathy 0 trials
- Infantile axonal neuropathy 0 trials
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Infectious neuropathy 2 trials
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Vasculitic neuropathy 2 trials
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Autoimmune neuropathy 1 trial
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Ischemic neuropathy 1 trial
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Sarcoid neuropathy 1 trial
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Motor peripheral neuropathy 0 trials · 1 incl. sub-types
9 sub-types
- Charcot-Marie-Tooth disease axonal type 2C 1 trial
- Charcot-Marie-Tooth disease type 4G 0 trials
- Charcot-Marie-Tooth disease type 5 0 trials
- Glossopharyngeal motor neuropathy 0 trials
- Hereditary motor and sensory neuropathy, Okinawa type 0 trials Sub-types →
- Motor nerve neuritis 0 trials Sub-types →
- Neuropathy, hereditary motor and sensory, type 6A 0 trials
- Neuropathy, hereditary motor and sensory, type 6B 0 trials
- Peripheral motor neuropathy, childhood-onset, biotin-responsive 0 trials
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Radiation-induced neuropathy 0 trials · 1 incl. sub-types
1 sub-type
- Radiation-induced plexopathy 1 trial
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Idiopathic small fibers neuropathy 0 trials
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Neuropathy in cryoglobulinemia 0 trials
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Neuropathy in endocrine disorder 0 trials
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Uremic neuropathy 0 trials
Most studied deeper sub-types
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Can a High-Tech wearable steady the steps of nerve damage patients?
Disease control Recruiting nowThis study tests a wearable device called the Leia sensory prosthesis in 80 adults with peripheral neuropathy, a condition that often causes balance problems and unsteady walking. Participants will either use the active device or a sham version for two months. The main goal is to…
Sponsor: MYNERVA AG • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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Could your own stem cells heal your brain? new trial tests it
Disease control Recruiting nowThis study is testing whether stem cells taken from a person's own bone marrow and then given back through the veins and nose can improve brain and nerve function. It includes 500 people with various conditions like stroke, Parkinson's, Alzheimer's, and nerve damage. The goal is …
Sponsor: MD Stem Cells • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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AI steps in to catch complications rheumatoid arthritis patients often miss
Diagnosis Recruiting nowThis study tests whether a generative AI tool can help doctors diagnose complications and co-existing diseases in people with rheumatoid arthritis. The AI reviews patient records and suggests possible issues like lung or heart problems. Doctors then decide if the AI's suggestions…
Sponsor: Guang'anmen Hospital of China Academy of Chinese Medical Sciences • Aim: Diagnosis
Last updated Jun 27, 2026 08:07 UTC
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Could an allergy pill protect cancer patients from nerve pain?
Prevention Recruiting nowThis study tests whether desloratadine, a common allergy medication, can prevent nerve damage caused by taxane chemotherapy in breast cancer patients. About 116 participants will receive either desloratadine or a placebo for 12 weeks while on chemotherapy. The goal is to see if t…
Phase 2 • Sponsor: Montefiore Medical Center • Aim: Prevention
Last updated Aug 28, 2026 00:00 UTC
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Smart insoles aim to stop diabetic foot ulcers before they start
Prevention Recruiting nowThis study tests if special sensor-equipped insoles can help prevent foot ulcers from coming back in people with diabetes and nerve damage. About 400 high-risk participants will use the insoles alongside standard care or just standard care alone. The goal is to see if the insoles…
Sponsor: Johns Hopkins University • Aim: Prevention
Last updated Jul 16, 2026 00:00 UTC
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Fish oil may shield cancer patients from chemo nerve pain
Prevention Recruiting nowThis study tests whether taking fish oil supplements can prevent nerve damage in the hands and feet caused by oxaliplatin chemotherapy in colorectal cancer patients. 120 participants will receive either fish oil or corn oil (placebo) during their treatment. The goal is to see if …
Sponsor: Vejle Hospital • Aim: Prevention
Last updated Jun 27, 2026 12:35 UTC
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Socks against side effects: simple stockings may shield nerves during chemo
Prevention Recruiting nowThis study tests whether wearing a compression stocking on one foot during antibody-drug conjugate (ADC) infusions can prevent peripheral neuropathy (nerve damage causing numbness or pain). Fifty-eight advanced cancer patients will wear a stocking on their left foot only, while t…
Sponsor: Sheng Zhang • Aim: Prevention
Last updated Jun 26, 2026 16:56 UTC
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Acupuncture and exercise may ease nerve pain from bladder cancer drugs
Symptom relief Recruiting nowThis study tests whether adding acupuncture to virtual exercise can help manage nerve pain caused by a specific bladder cancer treatment (EV-Pembro). About 50 adults with advanced bladder cancer will be split into two groups: one gets acupuncture plus virtual exercise, the other …
Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated Sep 12, 2026 00:00 UTC
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Freezing pain away: yale tests Nerve-Blocking procedure for Long-Term relief
Symptom relief Recruiting nowThis study will follow 80 people with chronic pain (like back, hip, or nerve pain) who are getting a procedure called cryoneurolysis, which uses cold to temporarily block pain signals. Researchers want to see if it leads to meaningful pain relief and better daily function over 12…
Sponsor: Yale University • Aim: Symptom relief
Last updated Aug 23, 2026 00:00 UTC
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Wearable gadget aims to stop falls in neuropathy patients
Symptom relief Recruiting nowThis study tests a device called Walkasins, worn on the lower legs, that vibrates to give sensory feedback about foot pressure. The goal is to see if using it daily for six months improves balance and walking in 200 adults aged 55+ with peripheral neuropathy. Participants will do…
Sponsor: RxFunction Inc. • Aim: Symptom relief
Last updated Jul 16, 2026 00:00 UTC
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Smart sock aims to steady shaky steps in nerve damage patients
Symptom relief Recruiting nowThis study tests a device called Walkasins, worn like an ankle strap and insole, that gives gentle vibrations to help people with peripheral neuropathy feel their feet better. The goal is to see if it improves walking, balance, and daily physical activity. Eighteen adults aged 60…
Sponsor: RxFunction Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Vibrating away chemo pain: simple hand device tested in new study
Symptom relief Recruiting nowThis small pilot study tests whether using a hand-held vibration device for just 3 minutes each day can safely reduce nerve pain and numbness in the hands caused by chemotherapy. Sixteen adults who finished chemotherapy at least 60 days ago will try the therapy at home. The main …
Sponsor: Indiana University • Aim: Symptom relief
Last updated Jun 27, 2026 12:39 UTC
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Can closing your eyes help you walk better? new rehab trial for nerve disorder
Symptom relief Recruiting nowThis study tests whether balance rehabilitation that changes how patients see (closing eyes, using a mask, or projecting moving dots) can improve walking stability better than standard rehab with eyes open. It includes 40 adults with chronic nerve damage who have trouble with bal…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 12:38 UTC
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Can tai chi and acupuncture soothe chemo nerve damage? new study investigates
Symptom relief Recruiting nowThis pilot study tests whether Tai Chi, alpha-lipoic acid supplements, and acupuncture can help ease chemotherapy-induced peripheral neuropathy (nerve pain, numbness, tingling) in people with gastrointestinal cancer. About 60 participants will try one or more of these approaches …
Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Symptom relief
Last updated Jun 27, 2026 12:08 UTC
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Tiny implant zaps away chronic joint pain in early trial
Symptom relief Recruiting nowThis early study tests a small device that sends gentle electrical pulses to nerves to relieve severe, long-lasting knee, elbow, or shoulder pain. About 30 adults with chronic pain will first try a temporary implant for up to 8 hours. If it works well, they can get a permanent ve…
Early phase 1 • Sponsor: Nervonik • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Shock therapy? electrical pulses aim to restore movement in paralysis
Symptom relief Recruiting nowThis early study tests whether a device that sends electrical pulses to muscles and the spinal cord can improve arm, hand, or leg movement in people with paralysis from spinal cord injury, stroke, or other nerve damage. Up to 64 participants will attend sessions five times a week…
Early phase 1 • Sponsor: Northwell Health • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Zapping away shingles pain: new trial tests pulsed radiofrequency
Symptom relief Recruiting nowThis study tests whether a noninvasive procedure called transcutaneous pulsed radiofrequency can reduce chronic pain from postherpetic neuralgia, a complication of shingles. The procedure delivers electrical pulses through electrodes placed on the skin over the painful area. Rese…
Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Spinal zap may soothe diabetic leg pain and boost circulation
Symptom relief Recruiting nowThis study tests whether a spinal cord stimulator—a device that sends mild electrical pulses to the spine—can reduce pain and improve blood flow in the legs of people with type 2 diabetes who have nerve pain. Researchers will enroll 25 adults with painful diabetic neuropathy and …
Sponsor: University of Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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Can tai chi ease chemo nerve damage? small study aims to find out
Symptom relief Recruiting nowThis study tests whether a 12-week virtual tai chi program is practical and acceptable for cancer survivors with chemotherapy-induced peripheral neuropathy (CIPN), which causes pain, numbness, and balance problems. Researchers plan to enroll 21 participants who have completed che…
Sponsor: Dana-Farber Cancer Institute • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Could turning nerve stimulation on and off beat continuous therapy for chronic pain?
Symptom relief Recruiting nowThis study looks at whether using a nerve stimulator in short bursts (30 seconds on, 90 seconds off) can provide the same or better pain relief as continuous stimulation. It involves 30 adults who have had a dorsal root ganglion stimulator for at least a year and report at least …
Sponsor: Rush University Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Chill out: cooling therapy may ease chemo nerve pain in breast cancer
Symptom relief Recruiting nowThis study tests whether a cooling device called hilotherapy can reduce nerve damage symptoms (like numbness, tingling, or pain) caused by taxane chemotherapy in breast cancer patients. About 60 participants will either receive the cooling treatment during each chemo session or s…
Sponsor: Nuran Ayşen Pamir Aksoy • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Magnetic device could ease nerve pain in veterans without drugs
Symptom relief Recruiting nowThis study tests whether a non-invasive magnetic stimulation device (AtMS) can reduce nerve pain caused by injury or surgery in veterans and active-duty military. 180 participants will receive either active, fixed, or sham stimulation over 16 weeks. Researchers will measure pain,…
Sponsor: Veterans Medical Research Foundation • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Common cholesterol drug may shield myeloma patients from chemo nerve pain
Symptom relief Recruiting nowThis study tests whether fenofibrate, a drug typically used for high cholesterol, can prevent or reduce nerve damage caused by a common chemotherapy regimen for multiple myeloma. The trial will enroll 44 newly diagnosed patients, half receiving fenofibrate alongside their standar…
Phase 4 • Sponsor: Tanta University • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Laser light at home could ease nerve pain in feet
Symptom relief Recruiting nowThis study tests a portable laser device that people use at home to temporarily relieve foot pain caused by idiopathic peripheral neuropathy. 32 adults with constant foot pain for at least 3 months will use the device twice daily for 21 days. The main goal is to see if at least 3…
Sponsor: Erchonia Corporation • Aim: Symptom relief
Last updated Jun 26, 2026 15:23 UTC
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Sound waves shed light on nerve and muscle health
Knowledge-focused Recruiting nowThis study uses ultrasound, a safe imaging technique that uses sound waves, to get detailed pictures and measurements of nerves and muscles. Researchers aim to collect normal values from healthy adults and compare them with data from people who have neuromuscular disorders. The g…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Sep 19, 2026 00:00 UTC
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Bedside test may end guesswork in nerve pain treatment
Knowledge-focused Recruiting nowThis study aims to see if a quick bedside sensory test can predict which painkiller—pregabalin, duloxetine, or a placebo—works best for people with nerve pain in their feet. About 190 adults with diabetic, chemotherapy-related, or idiopathic nerve pain will try each treatment for…
Phase 2 • Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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NIH launches data repository to fuel future research on rare nerve and muscle diseases
Knowledge-focused Recruiting nowThis study gathers medical information from 200 adults with possible nerve, muscle, or autonomic nervous system disorders who are not already in other NIH studies. Participants undergo standard tests like nerve conduction studies, EMG, and physical exams. The data is stored anony…
Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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New study aims to uncover nerve side effects of cancer drug
Knowledge-focused Recruiting nowThis study looks at how the drug enfortumab vedotin affects nerves in people with advanced or muscle-invasive bladder cancer. Researchers will use nerve tests and patient surveys to track changes over 9-15 weeks. The goal is to better understand and potentially reduce nerve damag…
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Scientists probe why spinal injury leads to debilitating nerve pain
Knowledge-focused Recruiting nowThis study looks at why some people develop nerve pain after a spinal cord injury. Researchers will use pain tests, nerve measurements, and heart rate checks in 300 participants to understand the underlying causes. The goal is to better classify pain types, not to test a new trea…
Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New study tracks hand nerve injury recovery over time
Knowledge-focused Recruiting nowThis study follows 100 adults who had surgery for traumatic nerve injuries in the hand or arm. Researchers will measure hand function, strength, and quality of life over time to better understand long-term recovery. The goal is to gather information, not to test a new treatment.
Sponsor: Suleyman Demirel University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New study aims to catch nerve damage early in chemo patients
Knowledge-focused Recruiting nowThis study looks at how nerves are affected in people who develop nerve damage from the chemotherapy drug cisplatin. Researchers will use a special test to measure nerve activity and compare it to normal nerves. The goal is to better understand this side effect and find early war…
Sponsor: Ka-Wai Ho • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Scientists hunt for genes behind chemo nerve pain in breast cancer patients
Knowledge-focused Recruiting nowThis study examines DNA from 575 breast cancer patients who received the chemotherapy drug paclitaxel. Researchers want to find genetic differences that explain why some patients develop nerve damage (peripheral neuropathy) while others do not. The goal is to identify biomarkers …
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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4,000 patients to help unlock secrets of nerve disease
Knowledge-focused Recruiting nowThis study is collecting information from 4,000 adults with peripheral neuropathy (nerve damage) to better understand the condition. Researchers will combine standard tests with nerve ultrasound to see if it helps diagnose and track the disease. No new treatments are being tested…
Sponsor: Casa di Cura Dott. Pederzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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New study eyes hidden diabetes damage in cystic fibrosis patients
Knowledge-focused Recruiting nowThis study looks at how often people with cystic fibrosis and diabetes develop complications like eye, kidney, and nerve problems. Researchers will also check blood pressure and cholesterol. The goal is to better understand these risks in a diverse group of 200 adolescents and ad…
Sponsor: Jaeb Center for Health Research • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Could a hormone be the hidden cause of diabetic nerve pain?
Knowledge-focused Recruiting nowThis study is investigating whether the hormone amylin, which is elevated in type 2 diabetes, is linked to peripheral neuropathy (nerve damage). Researchers will collect blood and skin samples from 40 adults with type 2 diabetes and mild-to-severe neuropathy. They will measure am…
Sponsor: Zabeen Mahuwala, MD • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Can sensors make braces better? new study aims to find out
Knowledge-focused Recruiting nowThis study checks if special sensors can reliably measure forces inside carbon fiber ankle-foot braces (orthoses). Researchers will test healthy volunteers and people with or without neuropathy who already use such braces. Participants will walk, sit, and stand while sensors reco…
Sponsor: University of Iowa • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Liquid nerve biopsy could unlock ALS secrets
Knowledge-focused Recruiting nowThis study is collecting nerve samples and biofluids from 400 people with ALS or peripheral neuropathies to find biological markers for early diagnosis and disease tracking. By analyzing individual cells, researchers hope to identify molecular changes that happen before symptoms …
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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What's a normal pupil? large study aims to find out in ICU patients
Knowledge-focused Recruiting nowThis study will collect pupil measurements from 1,000 patients in the neuro-intensive care unit using a device called a pupillometer. The goal is to establish what normal pupil size, reactivity, and neurological pupil index values are for critically ill patients. By gathering thi…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Sound waves vs. nerve disease: a new way to spot GBS and CIDP?
Knowledge-focused Recruiting nowThis study looks at whether ultrasound can detect nerve changes in people with Guillain-Barré syndrome (GBS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) earlier than standard tests. Researchers will compare ultrasound images with nerve conduction studies …
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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New study aims to unravel nerve damage in rare blood cancer
Knowledge-focused Recruiting nowThis study looks at why many people with Waldenström's macroglobulinemia, a rare blood cancer, develop nerve damage that can cause pain, numbness, and trouble moving. Researchers will examine 90 patients to find out how common this nerve damage is and what causes it. The goal is …
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:33 UTC