Lumbar spinal stenosis

This trial studies a device called coflex, a small implant placed in the spine after decompression surgery for lumbar spinal stenosis (a narrowing of the spinal canal that causes back and leg pain). The study includes 40 adults with moderate to severe stenosis and low back pain. …

This study tested a new way to set the breathing machine during back surgery. Instead of using standard settings, doctors adjusted the machine based on how stiff the patient's lungs were. The goal was to see if this approach could reduce lung problems after surgery. The study inv…

This study tests whether a standardized way of taking spine X-rays gives consistent results. 45 people with back or leg pain will have two sets of X-rays to see if the measurements match. The goal is to improve how doctors diagnose spinal instability.

This trial tests whether oxytocin nasal spray can prevent postoperative delirium—a state of confusion that can occur after surgery—in older adults undergoing orthopedic procedures. Participants aged 65 and older will receive the spray before the end of anesthesia and twice daily …

This study tested a new gel called Collabarrier® to see if it can prevent scar tissue from forming after back surgery for herniated discs or spinal stenosis. Sixty-nine adults having their first back surgery were randomly given either the new gel or an existing one. Researchers c…

This study looked at whether a lumbar epidural steroid injection can reduce restless legs syndrome symptoms in 45 adults with lumbar central spinal stenosis. Participants received a standard injection as part of routine care, and their restless legs severity, pain, disability, an…

This study tested a 6-week program that combines specific exercises with education to see if it improves walking ability in people with lumbar spinal stenosis and nerve-related leg pain. Fifty-one adults aged 50 and older took part. The intervention group received both exercises …

This study compared a newer, less invasive endoscopic surgery to standard open surgery for people with lumbar spinal stenosis, a condition that causes back and leg pain. 36 adults who needed surgery were randomly assigned to one of the two procedures. Researchers measured pain, w…

This study tested whether giving acetaminophen (Tylenol) through an IV works better than pills for pain after lumbar spine surgery. 166 adults having a specific type of back fusion surgery were randomly assigned to receive either IV or oral acetaminophen. The goal was to see if t…

This study looked at different rehabilitation programs for 90 adults who had back surgery for degenerative lumbar disease. The goal was to see which rehab approach best reduces nerve pain, helps patients regain function, and improves quality of life. Participants were randomly as…

This study compared two surgical approaches for people with a single level of lumbar spinal stenosis (a narrowed spine canal causing leg pain and trouble walking). 96 adults aged 40-75 were randomly assigned to receive either minimally invasive decompression and fusion or traditi…

This study compared two procedures for relieving pain from lumbar spinal stenosis, a common cause of back and leg pain in older adults. One group received a newer technique called erector spinae plane block, while the other got a standard caudal epidural steroid injection. Resear…

This study tested whether Opalmon tablets can improve symptoms and physical function in 107 adults with acquired lumbar spinal stenosis, a condition where the spinal canal narrows and causes leg pain when walking. Participants took the medication for 8 weeks, and researchers meas…

This study tested whether adding the steroid dexamethasone to a standard nerve block could reduce pain and inflammation after lumbar laminectomy (back surgery). Thirty-six adults undergoing surgery received either the nerve block with dexamethasone or without. The dexamethasone g…

This study looked at two types of surgery for people over 50 with a slipped vertebra (spondylolisthesis) and a narrowed spine canal (stenosis). One group had a smaller surgery to take pressure off the nerves (decompression alone), while the other had that plus a fusion with metal…

This study tested a new device called Ceragem Master V6 that gently stretches the spine in people with herniated discs or spinal stenosis. 60 adults were randomly assigned to use the new device or standard physical therapy. The goal was to see if the device could improve spine st…

This small study tested whether a spinal cord stimulator can reduce back and leg pain in people with lumbar spinal stenosis caused by epidural lipomatosis (fatty tissue buildup). Three adults with chronic pain received the device and were followed for 6 weeks. The main goal was t…

This completed study looked at 90 people with lower back pain from conditions like herniated discs or spinal stenosis. Researchers compared two different target areas for injecting numbing medicine during a lumbar spine block to see which provides better pain relief and blood flo…

This study tested whether a specific nerve block, called an erector spinae plane block, can lower the amount of morphine patients need after lumbar spine surgery. 100 adults having surgery for herniated discs or spinal stenosis were included. The block is given under ultrasound g…

This study tested whether an injection of amniotic fluid, a natural anti-inflammatory, works better than a standard steroid injection for chronic back and leg pain caused by spinal stenosis. Sixty-one adults who had not improved with other treatments were randomly assigned to rec…

This study tested whether letting doctors practice on a 3D virtual reality model of a patient's spine before a real injection makes the procedure faster and safer. Thirty adults with difficult-to-treat back pain took part. The main goal was to see if VR training reduced procedure…

This study looked at 20 people with lumbar spinal stenosis (a narrowing in the spine that can cause leg pain when walking) who were waiting for surgery. Researchers measured their walking patterns and asked about pain, function, and quality of life before and after the operation.…

This pilot study tested whether a larger trial is possible comparing two standard surgeries for lumbar spinal stenosis with a related condition called spondylolisthesis. The two procedures are decompression alone and decompression with fusion. The study enrolled 70 surgical candi…

This study explored how frailty affects people with lumbar spinal stenosis, a common age-related back condition. Researchers measured pain, balance, disability, fear of falling, and quality of life in 91 participants aged 45-80. The goal was to better understand frailty in this g…

This completed study from Turkey examined 81 adults aged 45–80 with lumbar spinal stenosis—a condition that causes back and leg pain when walking. Researchers measured pain, disability, sleep quality, depression, and a condition called central sensitization (where the nervous sys…

This study looked at whether manual therapy, exercise, and acupuncture can reduce pain and improve walking in older adults with lumbar spinal stenosis, a common cause of back and leg pain. Researchers enrolled 60 participants to see if a larger trial is possible. The goal is to f…

This study looked back at 25 years of medical records from 246 patients aged 50+ with lumbar spinal stenosis (a narrowing in the spine that can cause leg pain and trouble walking). Researchers compared patients who had a less invasive surgery (tubular decompression, with or witho…

This study looked at 50 people with lumbar spinal stenosis to see if simple decompression surgery or a more complex fusion surgery leads to better outcomes. Researchers measured pain, disability, quality of life, and movement using questionnaires and wearable sensors. The goal wa…

This study looked at 72 people with lumbar stenosis who had decompression surgery to relieve leg and back pain. Researchers wanted to see if the surgery also improved their posture, specifically a forward-leaning stance. They used special X-ray imaging to measure changes in spine…

This study looked at 39 people having lower back surgery for a herniated disc or spinal stenosis. Researchers checked for nerve pain before surgery and again 1, 3, 6, and 12 months after using a simple questionnaire. The goal was to see how common nerve pain is after surgery and …

This study looked at 40 adults with lumbar spinal stenosis (a narrowing in the spine that causes pain and trouble walking) who were scheduled for surgery. Researchers measured how fast they could walk before and after the operation using a 6-minute walk test. The goal was to see …

This study used MRI scans to measure the volume of spinal fluid in 40 adults before they received spinal anesthesia for surgery. Researchers wanted to see if the amount of fluid affected how high and how long the anesthesia worked. The goal is to help doctors tailor anesthesia do…

This study looked at 120 people aged 50 and older with low back pain to see how well MRI-based grading of lumbar spinal stenosis matches what patients report on disability and pain questionnaires. Researchers compared three common questionnaires (Oswestry Disability Index, Istanb…