New ventilator method may cut lung risks after spine surgery

NCT ID NCT07349719

Disease control Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new way to set the breathing machine during back surgery. Instead of using standard settings, doctors adjusted the machine based on how stiff the patient's lungs were. The goal was to see if this approach could reduce lung problems after surgery. The study involved 72 adults having lumbar spine surgery while lying on their stomachs.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: Dynamic compliance-guided ventilation (a procedure to adjust ventilator settings based on lung stiffness)
What this could lead to: If it works, this could lead to a simple way to reduce lung complications after back surgery, helping patients recover better.
What could go wrong: This is a small, early-stage study with only 72 participants. The results may not apply to all patients or surgeries, and the benefit may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

72 people

The number who actually took part.

Started

Jan 2026

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who will undergo lumbar stabilization in the prone position Exclusion Criteria: * Patients with ASA classification IV or higher * Patients with obesity (BMI\>30) or cachexia (BMI\<18) * Allergy to standard medications used during general anesthesia * Contraindications to PEEP (high intracranial pressure, bronchopleural fistula, hypovolemic shock, right heart failure) * Previous lung surgery (any) * Known serious heart disease defined as New York Heart Association class III or higher * Patients with severe asthma and COPD * Acute myocardial infarction within the last 12 months before surgery * Neuromuscular disease

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Conditions

The condition(s) this trial relates to.

Intervertebral Disc Displacement lumbar disk disease lumbar disk herniation, susceptibility to lumbar spinal stenosis Postoperative Complications Ventilator-Induced Lung Injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lumbar disc herniation Lumbar spine stenosis Postoperative complications Ventilator induced lung injury

New ventilator method may cut lung risks after spine surgery

What the study statuses mean