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Dysmenorrhea
MONDO:1060205A menstrual disorder characterized by pain during the menstrual cycle.
102 clinical trials for this condition and its sub-types, 48 tagged with Dysmenorrhea itself.
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Sub-types of Dysmenorrhea
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Primary dysmenorrhea 77 trials
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Secondary dysmenorrhea 2 trials
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New handmade IUD aims to stay put in women with adenomyosis
Disease control CompletedThis study tested a handmade frameless IUD that releases the hormone levonorgestrel in 15 women at high risk of IUD expulsion due to conditions like adenomyosis or heavy bleeding. The device was made by combining an anchor system with a standard IUD after removing its T-shaped ar…
Sponsor: Yu Wang • Aim: Disease control
Last updated Jun 27, 2026 12:05 UTC
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Can pelvic floor exercises plus taping or electrical current ease period pain?
Symptom relief CompletedResearchers are testing whether adding interferential current or kinesio taping to pelvic floor muscle exercises helps women with primary dysmenorrhea. Sixty women aged 18 to 30 will be randomly assigned to one of three groups: exercises alone, exercises plus interferential curre…
Sponsor: Istanbul Medipol University Hospital • Aim: Symptom relief
Last updated Sep 21, 2026 16:00 UTC
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Period relief in a pill? new study tests daily supplement for cramps and mood swings
Symptom relief CompletedThis study tested a daily dietary supplement (DITTO Cycle Supplement) in 40 women aged 18-45 who regularly experience period symptoms like cramps, bloating, fatigue, and mood swings. Over three menstrual cycles, researchers tracked changes in symptom severity and quality of life …
Sponsor: Muse Nutrition Ltd • Aim: Symptom relief
Last updated Aug 19, 2026 00:00 UTC
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Hand and foot pressure may soothe menstrual cramps, small study suggests
Symptom relief CompletedThis study looked at whether SuJok therapy—a technique that applies pressure to specific points on the hands and feet—can reduce period pain and improve quality of life in young women with primary dysmenorrhea (painful periods without an underlying medical cause). Researchers enr…
Sponsor: Muş Alparslan University • Aim: Symptom relief
Last updated Jul 10, 2026 00:00 UTC
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Seed cycling: a natural remedy for period problems?
Symptom relief CompletedThis study tests whether eating specific seeds at different times of the month can help women ages 18-45 with irregular periods, cramps, and PMS. Participants will eat flax and pumpkin seeds during the first half of their cycle, then switch to sunflower and sesame seeds during th…
Sponsor: Loma Linda University • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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VR goggles and music may soothe period pain, small study finds
Symptom relief CompletedThis study looked at whether watching a video through virtual reality goggles with music can reduce pain and improve sleep quality in women with period pain (dysmenorrhea). 77 women aged 15-49 with moderate to severe pain used either VR with music or just music alone for 3 days. …
Sponsor: Hasan Kalyoncu University • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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Mind over menstrual pain: imagining exercise may help
Symptom relief CompletedThis study tested whether combining motor imagery (mentally practicing movements) with gentle exercise can reduce menstrual pain and improve coordination. Forty-eight women with moderate to severe period pain were split into three groups: one did motor imagery plus exercise, one …
Sponsor: University of Valencia • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Back exercises may soothe menstrual cramps, study finds
Symptom relief CompletedThis study tested whether spinal stabilization exercises could help women with painful periods. Fifty women aged 18-30 with regular cycles and no childbirth history were split into two groups: one did the exercises, the other did not. Researchers measured pain, symptoms, and dail…
Sponsor: Sevtap Günay • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Back cracking for cramps? study tests spinal therapy for period pain
Symptom relief CompletedThis study looked at whether spinal manipulation combined with connective tissue massage can reduce pain, menstrual symptoms, depression, and sleep problems in women with primary dysmenorrhea (painful periods). Seventy-five women were split into three groups: one received both tr…
Sponsor: Istanbul University - Cerrahpasa • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Could a small device replace painkillers for period pain?
Symptom relief CompletedThis pilot study tested a portable TENS device for reducing menstrual pain in 34 women with primary dysmenorrhea. Participants used the device on their lower abdomen during pain episodes for up to three cycles. The goal was to see if this drug-free approach could ease pain and im…
Sponsor: Centro Universitario La Salle • Aim: Symptom relief
Last updated Jun 27, 2026 12:06 UTC
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Rose of jericho or deep breaths: simple fix for cramps?
Symptom relief CompletedThis study tested two non-drug approaches for severe period pain: placing a dried Rose of Jericho plant in water near the person, and practicing 4-7-8 breathing exercises. 100 women aged 18-35 with very painful periods took part over three cycles. Researchers measured changes in …
Sponsor: Çanakkale Onsekiz Mart University • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Yoga vs. exercise: which soothes endometriosis pain better?
Symptom relief CompletedThis completed study compared an 8-week online yoga program to a conventional exercise routine in 52 women with endometriosis. The goal was to see if yoga could better reduce pain and improve quality of life. Participants practiced meditation, breathing, and gentle poses, while t…
Sponsor: Beneficência Portuguesa de São Paulo • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Can simple stretches beat period pain? new study tests two Drug-Free options
Symptom relief CompletedThis study tested two non-drug treatments—post-isometric relaxation and simple stretching—to see which works better for period pain in young women. Forty-four unmarried women aged 18-30 with painful periods did one of the two exercises three times a week for eight weeks. The goal…
Sponsor: Khyber Medical University Peshawar • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Pilates put to the test for menstrual cramps
Symptom relief CompletedThis study looked at whether Pilates exercises can reduce pain and other symptoms of dysmenorrhea (period pain). Fifty-six women with menstrual pain were assigned to either mat Pilates, reformer Pilates, or a control group. Researchers measured changes in pain, fatigue, sleep qua…
Sponsor: Uskudar University • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Could a stiff c-section scar worsen period pain? scientists test the link
Knowledge-focused CompletedThis study looks at whether the mobility of a cesarean scar is related to the severity of menstrual pain in women who have had a C-section. Researchers will measure scar mobility, pain levels, and pressure sensitivity in 34 women aged 20–35 with regular cycles and period pain. Th…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Why do period pills fail some women? new study investigates
Knowledge-focused CompletedThis study looked at 70 women with severe menstrual pain to understand why some don't get relief from NSAIDs like naproxen. Researchers measured pain changes after taking the drug or a placebo and tested how the brain processes pain. The goal is to find out if central sensitizati…
Phase 4 • Sponsor: Mclean Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Survey reveals generational differences in menstrual management
Knowledge-focused CompletedThis completed study surveyed 1,200 women aged 18-55 to explore how different generations manage menstrual symptoms like cramps, pain, and related discomfort. Participants completed questionnaires about their symptoms, attitudes toward menstruation, sleep quality, physical activi…
Sponsor: Batman University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Scientists unravel the mystery of menstrual cramps and pain relief
Knowledge-focused CompletedThis study looked at 183 women with menstrual pain to understand why it happens and how naproxen (a common painkiller) relieves it. Using MRI scans, researchers measured uterine activity, blood flow, and oxygen levels before and after taking naproxen or a placebo. The goal is to …
Phase 4 • Sponsor: Endeavor Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Study reveals how much pain relief actually matters for period cramps
Knowledge-focused CompletedThis study looked at 100 women with primary dysmenorrhea (painful periods) to find out what amount of pain reduction is truly meaningful to them. Participants did an 8-week exercise program, and researchers measured pain and other symptoms using standard questionnaires. The goal …
Sponsor: Artvin Coruh University • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:00 UTC