Period relief in a pill? new study tests daily supplement for cramps and mood swings
NCT ID NCT07267728
First seen Jun 27, 2026 · Last updated Aug 18, 2026 · Updated 2 times
Summary
This study tested a daily dietary supplement (DITTO Cycle Supplement) in 40 women aged 18-45 who regularly experience period symptoms like cramps, bloating, fatigue, and mood swings. Over three menstrual cycles, researchers tracked changes in symptom severity and quality of life using questionnaires. The goal was to see if the supplement could make periods more manageable.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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Feb 2025
- Finished
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Jul 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female-at-birth, generally healthy * Aged 18-45 * In the last three menstrual cycles, has experienced three or more of the following symptoms associated with their menstrual cycle: Menstrual cramps, Bloating, Breast tenderness, Headaches, Fatigue, Muscle aches and/or joint pain, Cravings, Mood swings, Low mood, Feelings of anxiety, Irritability, Difficulty concentrating * Natural menstrual cycle or regular withdrawal bleeds if on hormonal contraception * Has a regular menstrual cycle length, between 21 and 35 days * Tracks their menstrual cycle and can predict their period dates * Willing to comply with study requirements * Willing to refrain from taking any other products, medications, or supplements that target menstrual health during the test period * No known allergies to the ingredients listed in the product Exclusion Criteria: * Anyone diagnosed with chronic conditions that may affect study outcome (e.g. heart conditions, diabetes, endocrine-related disorders, reproductive health-related cancers) * Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including oncological and psychiatric disorders * Women who are pregnant, breastfeeding, or trying to conceive * Anyone unwilling to follow the study protocol * Anyone in perimenopause, menopause, or experiencing menopausal-type symptoms * Started, changed, or stopped taking hormonal birth control in the last three months * Anyone with planned surgery during the study period * Anyone with a history of substance abuse * Anyone currently participating or planning to participate in a research study * Has a planned insertion or replacement of an IUD in the next 12 weeks
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Citruslabs
Las Vegas, Nevada, 89118, United States
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Other studies related to the condition(s) this trial covers.
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