Seed cycling: a natural remedy for period problems?
NCT ID NCT07052500
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether eating specific seeds at different times of the month can help women ages 18-45 with irregular periods, cramps, and PMS. Participants will eat flax and pumpkin seeds during the first half of their cycle, then switch to sunflower and sesame seeds during the second half, for three months. The goal is to see if this simple dietary change can make periods more regular and reduce symptoms.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Seed cycling (flax, pumpkin, sunflower, and sesame seeds)
- What this could lead to
- If it works, this could offer a simple, natural way to improve menstrual regularity and reduce cramps and PMS symptoms without medication.
- What could go wrong
- This is a small, early-stage trial with only 50 participants and no placebo group. Results may not apply to everyone, and some people may experience mild stomach issues or no benefit at all.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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Nov 2025
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Women ages 18-45 with an irregular menstrual cycle and/or menstrual cramps, and/or pre-menstrual symptoms. "Irregular"is defined as a cycle that deviates from the typical pattern of 21 to 35 days between periods * Access to an electronic device with a built-in health tracking app that can connect to the internet and is capable of reading QR codes * Speak and understandEnglish Exclusion Criteria: * Current or recent use (within the last 3 months) of hormonal birth control or hormone replacement therapy * Currently pregnant, lactating, or planning pregnancy between now and December 2025 * Active gastrointestinal (GI) condition * Currently consuming seed oil supplements * Allergic to flax seeds, pumpkin seeds, sesame seeds, or sunflower seeds * Unable to chew or swallow flax seeds, pumpkin seeds, sesame seeds, or sunflower seeds * Daily, regular consumption of flax seeds, pumpkin seeds, sesame seeds, or sunflower seeds
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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School of Allied Health Professions
Loma Linda, California, 92354, United States
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