Colorectal adenoma

This trial tests whether a simple clip-and-floss traction device can speed up the removal of large colon polyps using a technique called endoscopic submucosal dissection (ESD). About 280 people scheduled for ESD will be randomly assigned to receive either the traction device or s…

This study tested a new method called underwater endoscopic submucosal dissection (UESD) for removing large colon growths. Instead of using gas to inflate the colon, the doctor fills it with saline (salt water) to improve visibility and make the procedure easier. The trial involv…

This study tested a traditional Chinese medicine formula called modified Si Ni San in 32 adults who had colorectal polyps removed. The goal was to see if the herbal treatment could improve gut bacteria balance and reduce inflammation better than standard probiotics. Results may h…

This completed trial tested whether a 3D imaging device helps doctors more accurately classify colon polyps and adenomas during colonoscopy compared to standard 2D imaging. 460 adults with colorectal polyps were randomly assigned to either 3D or 2D imaging before polyp removal. T…

This trial tests how accurately an AI system, called GI Genius, can identify which polyps found during a colonoscopy are adenomas, the type that can become cancer. About 395 adults undergoing screening, diagnostic, or surveillance colonoscopy will receive the AI-assisted procedur…

This study tested whether a special light technology (enhanced white light endoscopy) helps doctors find more precancerous growths in the colon compared to standard colonoscopy. Over 800 adults aged 45 to 85 undergoing colonoscopy took part. The goal was to see if the enhanced li…

This study tested whether using a camera capsule (a pill you swallow) as a first test for bowel cancer screening could encourage more people to get screened and find more polyps or cancers. Over 2,000 people in Denmark took part. The goal was to see if this approach reduces the n…

This study tested whether an AI tool that highlights suspicious areas during colonoscopy helps doctors find more polyps. Over 400 adults aged 40-80 undergoing screening or diagnostic colonoscopy were randomly assigned to standard colonoscopy or AI-assisted colonoscopy. The main g…

This trial tests whether using a technique called hybrid argon plasma coagulation (h-APC) on the edges of the removal site can prevent colon polyps from growing back after endoscopic mucosal resection (EMR). EMR is a standard procedure for removing large polyps, but when polyps a…

This study looked at whether taking omeprazole (a heartburn drug) and low-dose aspirin together could help prevent colorectal polyps in people at high risk. Twenty-one adults with a history of multiple polyps took both pills daily for 25-45 days. Researchers collected tissue samp…

This study tested whether taking magnesium supplements could reduce the risk of colorectal cancer in people with a specific genetic makeup. Researchers gave 250 participants either magnesium or a placebo for 12 weeks and measured changes in colon tissue markers linked to cancer d…

This pilot study tested whether a mindfulness program could help reduce colorectal cancer risk factors in Black women aged 45-65 who live in high-crime Chicago neighborhoods and have had a colon polyp. Twenty-four women participated to see if the program was feasible and acceptab…

This study looks at whether a computer-aided diagnosis (CADx) system can help doctors better identify small colorectal polyps (5 mm or smaller) during a colonoscopy. Over 360 doctors will use the system to predict whether polyps are harmless or precancerous. The goal is to see if…

This study investigates whether women who have completed breast cancer treatment have a higher chance of developing colorectal polyps or colon cancer. Researchers will perform screening colonoscopies in 216 asymptomatic breast cancer survivors and check for abnormal growths. The …

This study looks at whether certain combinations of genetic variations, rather than a single gene, can increase the risk of colorectal cancer. Researchers will compare the DNA of 700 patients with strong family histories of the disease against 350 healthy controls. The goal is to…

This study reviewed the medical records of 255 adults who had colorectal polyps removed during a colonoscopy. The goal was to find out which factors, such as how the polyp was removed or its tissue type, make it more likely to come back. Researchers also tracked any complications…

This study looked at 80 adults aged 40-60 to see if sitting for long periods slows down gut transit time and changes gut bacteria in ways that could lead to colon polyps. Participants wore activity monitors, ate blue muffins to track digestion time, and provided stool samples. Th…

This study tested whether a short training video on 'blink features' (visual clues like redness or ulcers) could help medical students and non-gastroenterology trainees better detect cancer in images of colon polyps. 65 participants completed an online survey before and after wat…

This study looked at the gut bacteria of 1,757 people who had colon polyps or colorectal cancer in the past. The goal was to see if certain bacteria patterns could help predict who is at high risk for new polyps or cancer. Researchers hope this will lead to a simple, non-invasive…

This study looked at nearly 3,000 people who had non-advanced colon polyps (small, low-risk growths) found during their first screening colonoscopy. Researchers wanted to see if having more of these polyps increased the chance of developing advanced growths or cancer later. The g…

This study looked at why some people develop colorectal polyps (growths that can turn into cancer) and others do not. Researchers collected blood, urine, saliva, and tissue samples from over 8,000 adults getting a colonoscopy. They also gathered information about lifestyle and he…