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New light on colonoscopy: can enhanced imaging spot more polyps?

NCT ID NCT06979232

Diagnosis Sponsor: Shanghai Jiao Tong University School of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a special light technology (enhanced white light endoscopy) helps doctors find more precancerous growths in the colon compared to standard colonoscopy. Over 800 adults aged 45 to 85 undergoing colonoscopy took part. The goal was to see if the enhanced light improves detection of adenomas, which can turn into cancer.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Enhanced white light endoscopy (device)
What this could lead to
If successful, this imaging technique could help doctors find more precancerous polyps during routine colonoscopies, potentially preventing colorectal cancer.
What could go wrong
This is a completed device comparison study, so results are available. However, the benefit may be small or not apply to all patient groups or endoscopists.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

845 people

The number who actually took part.

Started

Sep 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 1\. Male or female aged 45 to 85 * 2\. Patients undergoing colonoscopy for colorectal cancer screening, positive fecal immunochemical test (FIT) results, gastrointestinal symptoms, or follow-up examination after colorectal polyp treatment * 3\. Capable of providing informed consent and agreeing to participate * 4\. Able and willing to follow all research processes Exclusion Criteria: * 1\. Participated in other clinical trials, signed informed consent form, and in the follow-up period of other clinical trials; * 2\. Participated in clinical trials of drugs and is in the discontinuation period of experimental or control drugs; * 3\. Have had drug or alcohol abuse or psychological disorders in the past five years. * 4\. Pregnant or lactating patients; * 5\. Known to have polyposis syndrome; * 6\. Patients with gastrointestinal bleeding; * 7\. Previous history of inflammatory bowel disease, colorectal cancer, or colorectal surgery; * 8.Patients with contraindications to tissue biopsy; * 9\. History of allergies to the ingredients in intestinal cleansers; * 10\. Individuals with conditions such as intestinal obstruction or perforation, toxic megacolon, heart failure (grade III or IV), severe cardiovascular disease, severe liver failure, or renal insufficiency, among others. * 11\. Researchers believe that patients are not suitable to participate in the trial.

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Conditions

The condition(s) this trial relates to.

colorectal adenoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal adenoma

Contacts and locations

Locations

  • Armed Police Forces Hospital of Sichuan

    Leshan, Sichuan, China

  • Chongqing General Hospital

    Chongqing, Chongqing Municipality, China

  • Ningbo Ninth Hospital

    Ningbo, Zhejiang, China

  • People's Hospital of Bayingolin Mongol Autonomous Prefecture

    Korla, Xinjiang, 841000, China

  • Taizhou First People's Hospital

    Taizhou, Zhejiang, 318020, China

  • The First People's Hospital of Lanzhou City

    Lanzhou, Gansu, 730050, China

  • The Third Affiliated Hospital of Heilongjiang University of Chinese Medicine

    Harbin, Heilongjiang, 150030, China

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