Can 3D vision spot hidden polyps better than standard colonoscopy?

NCT ID NCT06924489

Diagnosis Sponsor: Xijing Hospital of Digestive Diseases Source: ClinicalTrials.gov ↗

First seen Aug 18, 2026 · Last updated Aug 19, 2026 · Updated 1 time

Summary

This trial tests whether a 3D imaging device used during colonoscopy helps doctors find high-risk adenomas—polyps that could turn into cancer—better than the usual 2D view. Adults aged 18-75 scheduled for a diagnostic colonoscopy will be randomly assigned to either a 2D or 3D scope. The study compares how often each method detects high-risk adenomas and tracks any side effects for 30 days afterward.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: 3D imaging device used during colonoscopy
What this could lead to: If 3D imaging proves better at spotting high-risk adenomas, it could lead to more accurate colon cancer screening and fewer missed polyps.
What could go wrong: The benefit may be small or not clinically significant, and 3D devices could have technical limitations or higher costs. Adverse events during colonoscopy are possible but generally rare.

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Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 1,566 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18-75 years; * Patients with indications for colonoscopy and receiving diagnostic colonoscopy, without history of inflammatory bowel disease, colorectal cancer, polypectomy or polyposis syndromes; * Signing the written informed consent; Exclusion Criteria: * Patients with polyposis syndromes (e.g., Peutz-Jeghers syndrome, Cronkhite-Canada syndrome, familial adenomatous polyposis \[FAP\], Lynch syndrome, etc.); * Patients with a history of colorectal polypectomy and pathological diagnosed as adenoma; * Patients with a history of colorectal adenocarcinoma or alarming symptoms; * Patients with a history of inflammatory bowel disease; * Patients with mental illness or severe functional disorder who cannot cooperate with colonoscopy; * Patients with severe cardiopulmonary insufficiency; * Patients with severe coagulation disorders or high bleeding risk (platelets \<50×10⁹/L, INR \>1.5; discontinuation of antithrombotic drugs should follow the 2012 Japanese Guidelines for Gastroenterological Endoscopy in Patients Undergoing Antithrombotic Treatment and the2017 Appendix on Anticoagulants Including Direct Oral Anticoagulants; * Patients with severe electrolyte imbalances; * Patients with acute peritonitis or suspected intestinal perforation; * Patients with toxic megacolon; * Patients with stage 3 or higher hypertension (systolic blood pressure ≥180 mmHg or diastolic blood pressure ≥110 mmHg); * Patients with untreated severe abdominal hernia, intestinal obstruction; * Patients with intestinal strictures of any cause; * Pregnancy and lactation.

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Conditions

The condition(s) this trial relates to.

colorectal adenoma polyp of large intestine

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal adenoma Colorectal polyps

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

1 site. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Can 3D vision spot hidden polyps better than standard colonoscopy?

What the study statuses mean