Knee replacement pain study stopped early: did the drug help?

NCT ID NCT05644496

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a drug called ZYNRELEF can control pain and reduce the need for strong opioid painkillers after knee replacement surgery. It included 29 adults aged 35-70 with knee osteoarthritis. The study was terminated early, so results are limited.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Doctors Hospital

    Miami, Florida, 33146, United States

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