Weight loss pill combo may help teens keep pounds off

NCT ID NCT04298203

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether a combination of two weight-loss drugs, phentermine and topiramate, could help 100 teens with severe obesity keep weight off after losing it through a meal replacement program. The goal was to see if the medication could counteract the body's natural tendency to regain weight. The study focused on safety and changes in body fat, BMI, and related health measures.

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Conditions

The condition(s) this trial relates to.

morbid obesity Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States