New stent technique could reduce deadly rebleeding in liver cirrhosis

NCT ID NCT07587671

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a new procedure using a special stent (underdilated VCX-TIPS) with standard treatment (endoscopic banding plus beta-blockers) to prevent variceal rebleeding in people with cirrhosis. The new approach uses a smaller balloon to expand the stent, aiming to lower pressure in the liver's blood vessels while reducing side effects like brain confusion. 240 participants who have recovered from a first variceal bleed will be randomly assigned to one of the two treatments and followed for one year to see which better prevents death or rebleeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Underdilated VIATORR Controlled Expansion stent (a device placed in the liver to reduce pressure in blood vessels)

What this could lead to

If successful, this could offer a more effective way to prevent dangerous rebleeding from varices in cirrhosis patients, potentially reducing deaths and the need for repeat procedures.

What could go wrong

This is an early-stage trial with only 240 participants, so results may not apply to all patients. The underdilated stent might still cause liver problems or brain confusion (hepatic encephalopathy), and the procedure carries risks like any invasive surgery.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver esophageal varices esophageal varices with bleeding Fibrosis hepatic encephalopathy portal hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Second Affiliated Hospital of Chongqing Medical University

    Chongqing, 610041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital, Sichuan University

    Chengdu, 610041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • West China Xiamen Hospital, Sichuan University

    Xiamen, 610041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••