New trial aims to ease bladder troubles in Parkinson's patients

NCT ID NCT07187466

Not yet recruiting Symptom relief Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times

Summary

This study tests two treatments—mirabegron (a drug) and exercise-based behavioral therapy—for overactive bladder in people with Parkinson's disease. Researchers want to see if combining treatments helps those who don't respond to one alone. The trial will involve 146 participants and measure symptom changes over 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: mirabegron (Myrbetriq) and exercise-based behavioral therapy
What this could lead to: If successful, this could provide a clear treatment plan for managing overactive bladder symptoms in people with Parkinson's disease, improving their quality of life.
What could go wrong: This is a phase 4 trial with 146 participants, so results may not apply to everyone. The treatments may not work for all, and mirabegron can cause side effects like increased blood pressure or urinary tract infection.

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Conditions

The condition(s) this trial relates to.

overactive bladder Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OVERACTIVE BLADDER PARKINSON DISEASE

Contacts and locations

Locations

Atlanta VA Medical and Rehab Center, Decatur, GA

Decatur, Georgia, 30033-4004, United States
Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA

Philadelphia, Pennsylvania, 19104-4551, United States
VA Salt Lake City Health Care System, Salt Lake City, UT

Salt Lake City, Utah, 84148-0001, United States

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