Gut implant shows promise for diabetes and obesity control

NCT ID NCT07417683

First seen Feb 25, 2026 · Last updated May 13, 2026 · Updated 14 times

Summary

This study tests a new device called the Trans-Duodenal Barrier, a temporary implant placed in the upper small intestine for 6 months. It aims to lower blood sugar (HbA1c) and help with weight loss in adults with type 2 diabetes and obesity. Researchers will also check if it improves liver health in patients with MASH. The implant is removed after 6 months, and participants are followed for 4 more weeks.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Charite Universitätmedizin Berlin CVK

    Berlin, 13353, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Klinikum St. Georg Leipzig

    Leipzig, Saxony, 04129, Germany

    Contact Phone: •••-•••-••••

  • Knappschaft Kliniken Universitätsklinikum Bochum GmbH Medizinische Klinik

    Bochum, North Rhine-Westphalia, 44892, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sozialstiftung Bamberg

    Bamberg, Bavaria, 96049, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Städtisches Klinikum Dresden

    Dresden, Saxony, 01067, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Leipzig Medical Center, Department of Oncology, Gastroenterology, Hepatology and Pneumology

    Leipzig, Saxony, 04103, Germany

  • Universitätsklinikum Würzburg

    Würzburg, Bavaria, 97080, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitätsmedizin Mannheim

    Mannheim, Baden-Wurttemberg, 68167, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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