MASH
Clinical trials for MASH explained in plain language.
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New MASH drug OPK-88006 enters early human testing
Disease control Recruiting nowThis early-stage study tests a new drug called OPK-88006 in 30 people, first in healthy volunteers and then in those with MASH (a serious liver condition). The goal is to check safety, how the drug moves through the body, and early signs of liver improvement. Results will help de…
Matched conditions: MASH
Phase: PHASE1, PHASE2 • Sponsor: OPKO Health, Inc. • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Could a stomach tuck reverse fatty liver?
Disease control Recruiting nowThis study tests whether a minimally invasive procedure called endoscopic sleeve gastroplasty (ESG), which reduces stomach size by 70%, can help reverse fatty liver disease (MASH) in people with obesity. Researchers will compare ESG plus lifestyle changes to lifestyle changes alo…
Matched conditions: MASH
Phase: NA • Sponsor: Pichamol Jirapinyo, MD, MPH • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Old heart drug could be new hope against fatty liver
Disease control Recruiting nowThis study tests whether a low dose of digoxin, a drug normally used for heart problems, can help people with a severe type of fatty liver disease called NASH (also known as MASH). The trial will involve 144 adults with biopsy-confirmed NASH and liver scarring. Participants will …
Matched conditions: MASH
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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New Scope-Based ultrasound could spare patients liver biopsies
Diagnosis Recruiting nowThis study is testing a new way to measure liver scarring using an endoscopic ultrasound with special software. About 300 adults with suspected liver disease will undergo this new scan, a standard liver biopsy, and another non-invasive test. The goal is to see if the new techniqu…
Matched conditions: MASH
Sponsor: Olympus Corporation of the Americas • Aim: Diagnosis
Last updated Jun 26, 2026 16:57 UTC
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Fatty liver disease: a new biobank aims to unlock the secrets of a silent epidemic
Knowledge-focused Recruiting nowThis study creates a large database and biobank of people with nonalcoholic fatty liver disease (NAFLD), a condition where fat builds up in the liver. Researchers will collect medical data and biological samples over time to study how the disease develops, progresses, and respond…
Matched conditions: MASH
Sponsor: Fondazione Epatocentro Ticino • Aim: Knowledge-focused
Last updated Jul 23, 2026 00:00 UTC
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No treatment here: scientists Double-Check their own lab methods
Knowledge-focused Recruiting nowThis study is not testing a new drug or treatment. Instead, researchers want to make sure their lab tests and equipment give accurate and repeatable results when studying conditions like obesity, diabetes, heart disease, and bone loss. Up to 100 healthy volunteers and people with…
Matched conditions: MASH
Sponsor: Bettina Mittendorfer • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC